Project Grant R03DE034797
- The $296,171 Project Grant awarded on August 8, 2025 by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to design and evaluate an impedance-based bone assessment technology for characterizing trabecular bone microarchitecture. This technology is intended to address the limitations of current imaging techniques, like cone beam CT, in accurately quantifying bone quality, particularly in the trabecular...
- This $27,030 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, supports research to understand how biofilm formation and adhesion is affected by 3D-printed titanium surfaces used in dental implants. The key objectives are to develop experimental tools for measuring structural, deformation, and diffusive properties of single and multi-species oral biofilms on 3D-printed titanium...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $582,000 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to the University of Rochester. The grant, awarded on May 1, 2025, will support research aimed at understanding the mechanisms underlying peri-implantitis, an inflammatory condition affecting dental implants. The research will utilize a rat model of peri-implantitis to investigate the role of epigenetic factors, such as the...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,952,000 Project Grant under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121) to Matregenix Inc., a small disadvantaged business located in California. The grant supports the development of MATRINOVA, an animal-free, amino acid-based biodegradable barrier membrane for guided bone regeneration in dental and craniomaxillofacial surgeries. The research aims to create a membrane with a unique...
- The Project Grant awarded by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), provides $306,633 to Ther-Ai LLC to develop CRANIAMAP, a foundational software module that enhances auto-segmentation and landmarking capabilities for cone beam computed tomography (CBCT) scans. This SBIR Phase I project aims to outperform existing AI-based tools, achieving at least 90% accuracy in segmenting critical...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $298,942 Project Grant to Deltamed LLC on August 20, 2025. The grant funding will support the development of a novel "nanosponge prodrug delivery system" for the small molecule MK2 inhibitors apatinib and MMI-0100. The goal is to improve the circulation half-life and targeted delivery of these compounds to mitigate...
- The federal Project Grant award in the amount of $613,736 was provided by the National Institute of Dental and Craniofacial Research (NIDCR), which administers the Oral Diseases and Disorders Research federal grant program (CFDA 93.121). The grant was awarded to Cayman Chemical Co Inc., a for-profit company located in Ann Arbor, Michigan, to develop novel osteogenic small-molecule pharmacotherapies for dental bone regeneration. Specifically, Cayman Chemical will create novel EZH2 inhibitor...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $150,989 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to the Research Foundation for the State University of New York (RFSUNY), doing business as Stony Brook University. The grant aims to develop an automated tool to detect and characterize arterial calcifications in dental cone beam computed tomography (CBCT) scans, which can be indicative of cardiovascular disease. This research...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $421,800 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Midwestern University. The purpose of this 3-year grant, with a start date of September 7, 2023, is to develop hybrid hydrogel-based dental adhesives that are less vulnerable to hydrolytic degradation compared to current methacrylate-based alternatives. The goal is to create a truly biomimetic dental adhesive that can not only...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $422,665 Project Grant to Oregon State University (OSU) to develop an integrated dental plaque bioanalytical platform for point-of-care diagnostics of oral diseases. The project aims to detect and quantify hydrogen peroxide and lactate produced by beneficial and pathogenic oral bacteria, and establish a correlation between oral caries...
The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded Rytek Medical Inc. a $220,000 Project Grant on August 1, 2025. The grant supports research to evaluate CT/X-ray imaging-correlated impedance-based metrics for predicting surgical osseointegration and injury prevention in dental implant procedures. The project aims to develop innovative diagnostic technologies, such as an impedance-based bone assessment method for characterizing trabecular bone microarchitecture, to improve the accuracy of pre-operative assessments and reduce complications associated with dental implant surgeries. This research project, with a planned completion date of July 31, 2027, aligns with NIDCR's mission to advance fundamental knowledge and translate findings into prevention, early detection, and treatment strategies that improve oral health outcomes.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $220.0k | 7/25/25 |