This $3,999,999 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will fund the acquisition of a Glacios 2 cryo-electron microscope (cryo-EM) at the Icahn School of Medicine at Mount Sinai (ISMMS). The goal is to enable researchers throughout the institution to conduct high-resolution structural analysis of diverse biological systems and disease mechanisms using single-particle cryo-EM. This new instrument will provide a seamless workflow for ISMMS researchers to collect atomic-resolution cryo-EM data on-site, as well as transition to using nearby shared cryo-EM facilities. The award, made on August 15, 2024, will support the establishment of a comprehensive cryo-EM research infrastructure at ISMMS, including the microscope, sample preparation equipment, IT capabilities, service contracts, and staffing. This investment will enhance the NIH-funded research programs of numerous investigators at ISMMS studying a wide range of biological systems underlying human diseases.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $2.0m | 8/21/24 | ||
| Not listed | $2.0m | 8/15/24 |