This National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) Program (CFDA 47.070) Project Grant award of $329,099 to The Johns Hopkins University aims to develop new quantitative models to uncover the functional architecture of the brain. The project will specifically focus on understanding how brain computations are distributed during navigation in zebrafish and decision-making in rodents. Key objectives include: 1) Identifying the brain systems underlying navigation using advanced optical imaging techniques to capture simultaneous activity of neurons and glia across the entire zebrafish larval brain, and 2) Developing a multi-scale missing-neuron dynamical system model to reveal how the functional architecture supports visual decision-making in rodents. This research is expected to provide new insights into the flexibility and robustness of biological intelligence. The project is scheduled to run for 5 years from October 2024 through September 2029.
Generated 3/4/25, 7:05 AM