This $2,306,736 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) aims to reveal critical neural mechanisms for intelligent reward-driven learning and decision-making. The primary awardee, The Regents of the University of California, San Francisco (UCSF), will employ advanced recording techniques and an innovative foraging task to rigorously assess the relationships between value-guided decision-making and...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,860,153 Cooperative Agreement under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286) to The Regents of the University of California, San Francisco (UCSF). The goal of this 3-year project, starting August 2024, is to establish scalable tools that combine spatial transcriptomics and connectomics to map the synaptic connectivity of...
The National Institute of Mental Health awarded a three-year Project Grant totaling $3,618,976 to the University of California, Los Angeles under the Mental Health Research Grants program (CFDA 93.242) to develop in situ single-cell multi-omic and morphological profiling methods for mammalian brains. Specifically, the university will work to design photonic-indexing sequencing strategies to spatially barcode tissue with single-cell resolution, integrating techniques such as PI-ATAC-seq and...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $1,920,113 to the University of California, Berkeley (UC Berkeley) to conduct research on the anterior lateral prefrontal cortex (ALPFC), a region of the brain implicated in various mental health disorders. The key objectives of this 5-year project are to: 1) evaluate the domain-generality of ALPFC's function during relational reasoning tasks, 2)...
This federal Project Grant award for $124,205.00 from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), will support research to investigate how the hippocampus and primary visual cortex coordinate mental simulations during active behavior in freely moving rats. The award to the Regents of the University of California, San Francisco (UCSF) aims to provide key insights into the neural basis of mental simulations, which could lead to a better...
This $580,000 Project Grant from the National Science Foundation Division of Information and Intelligent Systems will fund research to develop more biologically realistic computational models of the primate visual system. Awarded under the Computer and Information Science and Engineering program (CFDA 47.070), the grant supports work at the University of California, San Diego from September 15, 2022 to August 31, 2025. The research aims to incorporate key features of human vision missing from...
This federal Project Grant award under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, funded by the National Institute of Neurological Disorders and Stroke (NINDS), supports research to optimize in vivo 2-photon voltage imaging methods for measuring sensory and cognitive signals in the somatosensory cortex of awake, behaving mice. The $399,077 award, made on July 1, 2024, will enable the development and calibration of methods to detect...
The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $1,852,675 under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to the University of California, Los Angeles from August 1, 2022 to July 31, 2025. The award will support the development of light field tomographic microscopy for kilohertz volumetric imaging of neuronal action potentials in awake behaving mice. Specifically, the...
This $660,000 Project Grant was awarded by the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CFDA 47.070) Federal Grant Program. The award supports a collaborative research project between the Allen Institute in Seattle, Washington and partners in Germany to develop computational models of neural representation and inter-areal communication in the mouse visual cortex. The key products and services to be delivered under this grant include: 1)...
This $1,999,635 project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke (NIH NINDS) will fund research into understanding feedforward and feedback signaling between neuronal populations. The grant was awarded to Albert Einstein College of Medicine on March 15, 2022 for a period ending February 28, 2025. The project aims to advance understanding of how feedforward and feedback signaling work together in the visual system by analyzing...