Project Grant RF1AG097882
- Federal Grant Award Summary Northwestern University's Sponsored Research Division received a $1.34 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective February 15, 2026, through November 30, 2030. This award supports continuation of a longitudinal cohort study examining aging-in-place and long-term care (AIP/LTC) decision-making and implementation among older adults with Alzheimer's dementia. The project follows 293...
- Federal Grant Award Summary The National Institute on Aging awarded a $656,829 Project Grant to the University of Rochester effective January 1, 2026, under the Aging Research program (CFDA 93.866) to investigate the selective vulnerability of the fronto-insular network (FIN) in aging and Alzheimer's disease (AD). The five-year research initiative, concluding December 31, 2030, combines in vivo structural, functional, and molecular analyses with behavioral assessments in mouse models to...
- Federal Project Grant Summary New York University School of Medicine received a $6.2 million Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 15, 2025 through May 31, 2030. The research initiative, titled "Peripheral Immunity and the Aging Brain," investigates the relationship between circulating vascular and immune dysfunction markers—specifically platelet aggregation and neutrophil activity—and...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded J. David Gladstone Institutes a Project Grant of $1,459,072 on August 1, 2025, under the Aging Research program (CFDA 93.866) to conduct research on Alzheimer's Disease (AD)-related neurological dysfunction. The research will deliver scientific knowledge and methodological innovations focused on understanding how inhibitory interneurons—specifically parvalbumin (PVALB) and somatostatin (SST) cell types—contribute...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $293,454 Project Grant to the University of Wisconsin–Milwaukee, effective January 15, 2026 through December 31, 2030, under the Aging Research program (CFDA 93.866). This award supports a neuroscience research initiative investigating how older age affects memory generalization—the cognitive ability to integrate separate experiences into unified knowledge to make informed inferences and decisions. The research...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $137,245 Project Grant to New York University School of Medicine on July 15, 2026, under the Aging Research program (CFDA 93.866). This research project, scheduled for completion on April 30, 2031, investigates the obesity paradox phenomenon observed in older end-stage kidney disease (ESKD) patients with cognitive impairment and dementia/Alzheimer's disease (AD). The award supports a comprehensive research initiative...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of South Florida $3.297 million under the Aging Research program (CFDA 93.866) for a four-year project period (September 1, 2025 – August 31, 2029) to develop novel peptidomimetic biomaterials that inhibit amyloid-beta (Aβ42) aggregation in Alzheimer's disease. The research deliverables include the rational design and characterization of structurally related analogues to a lead compound that stabilizes Aβ...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $2.003 million Project Grant to the University of Pittsburgh under the Aging Research program (CFDA 93.866) on September 15, 2025, with a completion date of August 31, 2029. This award funds research to characterize white matter injury in Alzheimer's disease (AD) and its role in cognitive decline. The study employs a novel, spatially precise neuroimaging methodology called Unhealthy White Matter Connectivity (UWMC) to...
- Federal Grant Award Summary The National Institute on Aging awarded University of Massachusetts Medical School a Project Grant of $452,783 under the Aging Research program (CFDA 93.866) to conduct biomedical research on molecular mechanisms of neuronal cell death and neurodegeneration. The award period runs from June 1, 2026, through May 31, 2028. The project delivers research services focused on understanding how to protect the brain from Alzheimer's disease by investigating the relationship...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded University of California, Irvine $3.22M under the Aging Research program (CFDA 93.866) for a project grant commencing September 15, 2025, with completion scheduled for August 31, 2029. This project will deliver biomedical research services focused on understanding the role of the retrosplenial cortex in Alzheimer's disease (AD) pathogenesis. The research will establish the mechanisms by which neuronal hyperexcitability...
The National Institute on Aging (NIA) awarded New York University School of Medicine a $3.55 million Project Grant under the Aging Research program (CFDA 93.866) to investigate the curse of choice phenomenon in elderly populations, particularly those experiencing cognitive decline. The four-year project, initiated July 15, 2026, and concluding June 30, 2030, delivers a comprehensive research program examining how decision quality deteriorates as the number of available options increases—a problem with documented impacts on seniors' costs and quality of life. The research will produce scientific deliverables including empirical demonstration of the hyperbolic relationship between choice efficiency and choice set size; quantification of age-related cognitive impairment effects on decision performance; characterization of individual susceptibility through neuropsychological phenotyping; identification of cortical mechanisms underlying the dysfunction; and validation of theory-driven remedial strategies. The project's practical output will include development of a new decision-support tool for deployment on government and private websites serving elderly users, designed to mitigate choice overload. By combining neurobiological investigation with applied intervention design, the award addresses the NIA's strategic priority of understanding aging processes and improving quality of life for older adults. The research findings will establish foundational knowledge for both human neuroimaging studies and future animal model investigations of choice-related cognitive decline, contributing to the broader portfolio of aging-related disease prevention and treatment research supported under CFDA 93.866.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.6m | 7/10/26 |