Project Grant RF1AG093965
- The National Institute on Aging (NIA) awarded a $2,151,314 Project Grant to the University of Missouri System under the Aging Research program (CFDA 93.866) to conduct research on the effects of fine particulate matter (PM) exposure on small cerebrovascular inflammation and cognitive dysfunction. The 3-year project aims to investigate how PM exposure induces sex-specific inflammatory responses mediated by TNF-alpha in males and IL-6 in females, leading to cognitive impairment. The research...
- This Project Grant from the National Institutes of Health's National Institute on Aging will fund research totaling $4,188,512 to the University of California, Davis from September 2022 through August 2025. The grant is part of the Aging Research program (CFDA 93.866), which supports biomedical, social, and behavioral research on aging processes and diseases affecting older populations. Specifically, the University of California, Davis will investigate the hypothesis that ultrafine particulate...
- The Project Grant titled "The Role of Neighborhood Social Exposome Dynamics in Risk and Resilience to Alzheimer's Disease and Related Dementias" was awarded by the National Institute on Aging (NIA), under CFDA Program 93.866 - Aging Research. The $3,039,714 grant, with a performance period from September 15, 2025 to September 14, 2029, will investigate the pathways between 30 years of neighborhood-level social exposome change, individual modifiable Alzheimer's disease and related...
- This Project Grant award from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), will fund a research project to investigate how environmental exposures such as temperature, greenspace, and the built environment influence cognitive function and dementia risk. The $5,164,012 award to the University of California, Davis will support a study using data from the Nurses' Health Study II and Rush University cohorts to estimate the links between...
- This $3,013,265 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA Program 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders will fund a research study to investigate the causal role of particulate matter components on Lewy body dementia. The award was granted to The Trustees of Columbia University in the City of New York, who will utilize large-scale epidemiological data, advanced statistical methods,...
- The National Institute on Aging (NIA), under the federal Aging Research grant program (CFDA 93.866), awarded a $1,703,626 Project Grant to the University of North Dakota (UND) Division of Research & Economic Development. The grant, effective September 1, 2023 through August 31, 2026, will fund research to investigate the potential link between lung dysfunction and the progression of Alzheimer's disease (AD). Key objectives include: Characterizing the temporal changes in AD-related lung...
- This $2,107,715 Project Grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) to the Regents of the University of Michigan aims to determine the extent to which exposure to hurricanes affects mortality among older adults living with Alzheimer's disease and related dementias (ADRD). The project will: 1) Examine all-cause mortality following hurricane exposure and identify associated causes of death among the ADRD population; 2) Determine the living environments...
- This federal Project Grant award from the National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, provides $667,664 to the University of Pittsburgh to study the impacts of air pollution and cigarette smoke on lung aging. The project, running from August 2025 to July 2027, will utilize human organoid and precision cut lung slice models to define how particulate matter (PM2.5) and cigarette smoke exposure influence mitochondrial dysfunction and cellular...
- This $4,260,300 project grant from the National Institutes of Health's National Institute on Aging will fund research under the Aging Research program (CFDA 93.866) to investigate the association between in utero environmental exposures and life-course cognition and prodromal Alzheimer's disease in midlife. The Public Health Institute will leverage existing data and biospecimens from the 50+ year follow up of the Child Health and Development Studies birth cohort to conduct targeted and...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $1,625,947 to the University of Rochester to conduct research on the relationship between air pollution-derived iron exposure, poverty-related stress, and Alzheimer's disease risk. The key objectives are to evaluate whether ambient and subway-level iron exposure leads to...
This $3,264,260 Project Grant award from the National Institute on Aging (NIA) under CFDA 93.866 (Aging Research) aims to determine whether olfactory impairment caused by exposure to ambient fine particulate matter (PM2.5) pollution is a causal factor in the development of late-onset dementia, including Alzheimer's disease. The award will fund a comprehensive research project conducted by the University of Maryland, Baltimore to investigate the role of the cGAS/STING/IKK2/NF-κB inflammatory pathway in olfactory dysfunction and its progression to neurodegeneration and dementia. The project will utilize mouse models to thoroughly test this hypothesis across three research aims over the award period from September 2025 to August 2029. The findings are expected to advance scientific understanding of the pathogenesis of PM2.5 exposure-related and unrelated dementias, and inform the development of early diagnostic and intervention approaches.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.3m | 9/5/25 |