The National Institute on Aging (NIA) awarded a Project Grant to Emory University under the Aging Research Federal Grant Program (CFDA 93.866) to investigate the link between air pollution exposure, the blood and brain metabolome, and their effects on Alzheimer's disease and related dementias. The total grant award is $2,329,825.00 with a project period from September 2024 to April 2029. The key objectives of this research project are to: 1) identify which specific components of fine particulate...
This Project Grant from the National Institutes of Health's National Institute on Aging will fund research totaling $4,188,512 to the University of California, Davis from September 2022 through August 2025. The grant is part of the Aging Research program (CFDA 93.866), which supports biomedical, social, and behavioral research on aging processes and diseases affecting older populations. Specifically, the University of California, Davis will investigate the hypothesis that ultrafine particulate...
This Project Grant award, valued at $1,532,878.00 and awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, aims to quantify the impact of combined environmental stressors on stroke and vascular risk factors for Alzheimer's disease-related dementias (ADRD) among diverse racial and ethnic populations. The research will leverage resources from three...
The National Institute on Aging (NIA) awarded a $2,151,314 Project Grant to the University of Missouri System under the Aging Research program (CFDA 93.866) to conduct research on the effects of fine particulate matter (PM) exposure on small cerebrovascular inflammation and cognitive dysfunction. The 3-year project aims to investigate how PM exposure induces sex-specific inflammatory responses mediated by TNF-alpha in males and IL-6 in females, leading to cognitive impairment. The research...
This federal Project Grant award of $1,205,827.00 from the National Institute on Aging (NIA) under CFDA Program 93.866 Aging Research aims to examine the role of the environmental exposome as a risk factor for Alzheimer's disease (AD) in non-Hispanic Whites, African Americans, and Mexican Americans. The project will utilize blood samples from 3,000 participants in the ongoing Health & Aging Brain Study - Health Disparities Study (NIA, U19AG078109) to investigate environmental exposures and...
This federal Project Grant award of $822,643.00, awarded by the National Institute on Aging under the Aging Research program (CFDA 93.866), will fund a research project to investigate how chronic exposure to common environmental neurotoxicants like lead, cadmium, and arsenic impact brain aging and the risk of late-onset Alzheimer's disease (LOAD). The researchers at Boston University Medical Campus, the prime awardee, will use innovative mouse models developed by the Model-AD Consortium to study...
The National Institute on Aging (NIA) awarded a $3,925,264 Cooperative Agreement (CFDA 93.866 - Aging Research) to the University of New Mexico Health Sciences Center (UNM HSC) to conduct preclinical research on the impacts of emerging environmental exposures, including wildfire smoke, microplastics, and heavy metals, on brain aging and the development of Alzheimer's disease and related dementias (ADRD). Under this 5-year award, the research team will use complementary mouse models to assess the...
The National Institute on Aging (NIA) awarded a $2,377,269 project grant (CFDA 93.866 - Aging Research) to Trustees of Boston University to evaluate how environmental factors impact cognitive health and risk of Alzheimer's disease and related dementias (ADRD) among racially and ethnically diverse older adult populations. The 5-year project, titled "Environmental Resources for Individual Cognitive Health/Resilience (ENRICH)," will leverage data from five NIH-funded cohorts (total...
The National Institute on Aging awarded a $2,278,304 Cooperative Agreement grant (CFDA 93.866 - Aging Research) to Emory University to investigate the molecular mechanisms linking exposure to air pollution components and the development of Alzheimer's disease and related dementias (AD/ADRD). The project, titled "IMPACT-ADRD: Investigating the Multi-Omics Perturbations Associated with Complex Environmental Toxicants and Their Contribution to Alzheimer's Disease and Related Dementias,"...
This three-year, $4.84 million project grant from the National Institute on Aging, part of the Department of Health and Human Services, will fund research at The Johns Hopkins University to investigate the neurological effects and cumulative risk of neurodegenerative disease from exposure to metal mixtures. Specifically, the researchers will examine the biological mechanisms by which exposure to mixtures of lead, arsenic, cadmium, and chromium during adulthood and early development cause...