Project Grant RF1AG079917

Award Date 9/15/23
Completion Date 8/31/26
Dollars Obligated $2.6M
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
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The National Institute on Aging (NIA) awarded a $537,000 Project Grant under the Aging Research federal grant program (CFDA 93.866) to Brigham & Women's Hospital Inc. (a subsidiary of Partners Healthcare System Incorporated) to culturally adapt and pilot a social network approach to deliver a sleep health and mindfulness program to cognitively unimpaired older adults in low-income housing in Boston. The project aims to improve sleep, quality of life, and cognitive function in this...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), provides $698,870.00 to study the effects of thalamic stimulation on sleep oscillations in humans. The research aims to investigate how thalamic stimulation, a potential therapeutic intervention, impacts sleep spindles and other sleep-related brain activity. This 5-year project will involve two cohorts: 50...
This Project Grant award from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), is focused on assessing whether genetic risk variants for Alzheimer's disease (AD) have a pleiotropic effect on sleep. The primary objectives are to conduct in silico variant-to-gene mapping analysis to identify potential shared genetic factors underlying AD and sleep phenotypes, and to use CRISPR in zebrafish models to directly evaluate the impact of putative AD...
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This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $1,498,158 to Synaptic Health LLC to develop a novel closed-loop feedback neuromodulation system to improve slow wave sleep in Alzheimer's disease patients. The goal of this Phase I project is to create a testable prototype that can sense sleep architecture and provide peripheral neuromodulation stimulation to individuals over 65, a high-risk group for Alzheimer's disease. Successful...
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