Project Grant K23AG088497

Award Date 8/15/24
Completion Date 5/31/29
Dollars Obligated $383K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Chicago, IL 60611, USA
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This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $684,924 to Northwestern University to conduct research on the relationship between the noradrenergic (NA) system, sleep quality, and cognitive function in older adults with insomnia. The project aims to systematically characterize central and peripheral measures of the NA system and assess their association with sleep quality and cognitive performance in older adults with insomnia, as well as...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $258,498.00 to the University of California, Los Angeles (UCLA) to investigate the biological pathways linking sleep health to Alzheimer's disease and cognitive decline. The key objectives are to: Use a multi-omics approach to analyze methylation and metabolomics data associated with short sleep and insomnia among a high-risk Hispanic population, and compare the results to Alzheimer's...
This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $129,659 to The Johns Hopkins University to conduct a longitudinal study examining the relationship between physical activity, sleep, brain network connectivity/microstructure, and cognitive resilience in aging and preclinical Alzheimer's disease. The research aims to identify modifiable lifestyle factors and neuroimaging biomarkers that may enhance cognitive resilience and help elucidate the...
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This Project Grant award from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), is focused on assessing whether genetic risk variants for Alzheimer's disease (AD) have a pleiotropic effect on sleep. The primary objectives are to conduct in silico variant-to-gene mapping analysis to identify potential shared genetic factors underlying AD and sleep phenotypes, and to use CRISPR in zebrafish models to directly evaluate the impact of putative AD...
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