Project Grant R01AG087163

Award Date 12/15/24
Completion Date 11/30/29
Dollars Obligated $780K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Aurora, CO 80045, USA
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This federal Project Grant award, R01AG087163, in the amount of $780,466.00, was provided by the National Institute on Aging under the Aging Research program (CFDA 93.866). The grant aims to develop digital biomarkers using single-channel sleep electroencephalography (EEG) to monitor brain health and detect preclinical neurodegeneration, with a focus on Alzheimer's disease. The research team, led by the University of Colorado-Denver, will utilize over 15,000 sleep recordings from existing cohorts to train and validate predictive models as the basis for these novel digital biomarkers. The goal is to create accessible, wearable technology capable of assessing pathological brain aging and cognitive decline through analysis of sleep-dependent memory processing circuits. The Washington University has been awarded a sub-grant under this project to provide specialized research services and expertise. The overall award duration is from December 2024 to November 2029.

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