Project Grant R61MH142354
- The National Institute of Mental Health awarded the University of Pittsburgh $1,004,971 through the Mental Health Research Grants program (CFDA 93.242) on April 8, 2026, to develop a platform for measuring and analyzing brain activity, cognitive states, behavior, and physiology during multiday neural recordings in individuals undergoing surgical treatment for epilepsy. The project will integrate wearable technology and artificial intelligence for behavioral and physiological monitoring alongside...
- The National Institute of Mental Health awarded California Institute of Technology $467,500 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate mechanisms of hypothalamic neuronal circuit development in zebrafish larvae. The research will map the architecture and connectivity of hypothalamic neurons expressing hypocretin, a neuropeptide that promotes arousal in both zebrafish and mammals. Using the Brainbow technique, researchers will label...
- The National Institute of Mental Health awarded the University of Southern California $751,034 on August 6, 2026, under the Mental Health Research Grants program (CFDA 93.242) to support a neuroscience research project examining how the brain processes uncertainty in noisy, dynamically changing environments. The project, titled "Unraveling Neural Mechanisms Underlying Learning in a Noisy, Dynamically Changing World," investigates computational and neural mechanisms by which the brain...
- The National Institute of Mental Health awarded Scripps Research Institute $878,601 on April 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to support structural remodeling of neural circuits via multisynaptic boutons. The research uses three-dimensional electron microscopy at nanometer resolution to reconstruct neuronal connectomes, individual synapses, and glia in the mammalian brain. The work combines 3D-EM with chemogenetic techniques for labeling cellular ensembles...
- The National Institute of Mental Health awarded the University of California, Los Angeles $444,845 under the Mental Health Research Grants program (CFDA 93.242) on September 1, 2026, to conduct a two-year study examining intra-individual determinants of neural oscillation phenomena. The funded research deploys multi-sensor measurements to concurrently capture objective measures of arousal (heart rate, heart rate variability, galvanic skin response, pupil metrics), motor activation (body, limb,...
- The National Institute of Mental Health awarded the University of Southern California $1.105 million on August 7, 2026, under the Mental Health Research Grants program (CFDA 93.242) to establish a global framework for harmonized functional MRI analysis in psychiatry. The project will harmonize resting-state fMRI datasets across eight psychiatric and neurodevelopmental disorders—schizophrenia, bipolar disorder, post-traumatic stress disorder, major depression disorder, obsessive compulsive...
- The National Institute of Mental Health awarded The Leland Stanford Junior University $426,991 under the Mental Health Research Grants program (CFDA 93.242) on August 3, 2026, to support research decoding medial prefrontal cortex (MPFC) plasticity across developmental life stages. The recipient is investigating critical periods of synaptic plasticity in the MPFC using high-throughput assays measuring long-term potentiation in mouse brain slices via multielectrode recording arrays. Aim 1 maps...
- The National Institute of Mental Health awarded New York University $435,974 on May 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop computational models that quantify individual differences in learning and decision-making and predict psychiatric symptoms. The award funds development of a novel computational framework combining recurrent neural networks and dynamical systems theory to model reward learning processes at the individual level rather than group...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $433,125 Project Grant to the University of California, Los Angeles (UCLA) under the Mental Health Research Grants program (CFDA 93.242) for the period September 1, 2025 through August 31, 2027. This research project investigates inter-brain synchrony as a neural mechanism underlying social connection deficits in schizophrenia—a core symptom of the disorder that current treatments fail to address. The study will...
- The National Institute of Mental Health awarded the University of California, Berkeley, $210,915 under the Mental Health Research Grants program (CFDA 93.242) on August 1, 2026. The award funds an 8-week remote summer workshop series that trains early-, mid-career, and senior-level social and behavioral scientists in machine learning and emerging artificial intelligence technologies, including generative AI and large language models. The curriculum begins with Python programming from a data...
The National Institute of Mental Health awarded California Institute of Technology $1,417,650 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop instrumentation for synchronized multimodal recording and analysis of human behavior and neural activity during complex, unstructured tasks. The project develops a system to acquire and synchronize behavioral data streams including head-mounted eye tracking to monitor gaze position, egocentric and allocentric video and audio, and wearable biophysiological sensors. Artificial intelligence methods will automatically label the collected data, including identification of fixated objects, audio transcription, and behavioral state classification. This system will be integrated with large-scale single-neuron recordings from the brains of epilepsy patients, enabling study of task control—the flexible sequencing of brief tasks to achieve goals—in human cognition. The research addresses a fundamental gap: current constrained cognitive tasks do not capture task control mechanisms, limiting understanding of deficits in patients with frontal cortex lesions or neuropsychiatric disease who fail to properly sequence behaviors despite intact performance of individual simple tasks. The award is structured as a Project Grant with a period of performance from September 1, 2026, through May 31, 2029. Work is performed in Pasadena, California. The project operates as part of the Brain Initiative's Brain and Behavior Quantification and Synchronization Consortium.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.4m | 8/26/26 |