This Project Grant award, with a total funding amount of $369,823, was made by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award will support research by the University of South Florida to investigate the role of SARS-CoV-2-induced cellular senescence in the development of Alzheimer's disease. The project aims to explore how SARS-CoV-2...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the federal Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research to investigate the mechanisms by which prior SARS-CoV-2 infection influences the risk of vascular contributions to cognitive impairment and dementia (VCID). The $1,120,805 award, with a project period from July 15, 2024 to June 30, 2025, aims to determine how...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides funding to the University of South Florida to investigate the molecular mechanisms underlying neurological sequelae, known as Neuro-COVID, that can occur following SARS-CoV-2 (COVID-19) infection. The $3,659,973 award, spanning from September 2024 to May 2029, aims to characterize the age-dependent neuroinflammation and tau pathology accelerated by COVID-19 infection, as well as validate...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $414,191 to Drexel University to investigate the interplay between polymorphic alpha-synuclein (α-syn) fibril conformation and cell-dependent pathology in synucleinopathies, including Lewy body dementia, Parkinson's disease, and multiple system atrophy. The research aims to...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will support research to investigate the mechanisms by which SARS-CoV-2 infection can lead to lasting neurological problems, known as "post-acute sequelae of COVID-19" (NEUROPASC), in COVID-19 survivors. The $801,329 award, with an initial period of performance...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $655,329 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Albert Einstein College of Medicine in Bronx, NY. The grant will fund research to determine the role of the GPNMB gene in the pathogenesis of Parkinson's disease, Lewy body dementia, and related synucleinopathies. The research will integrate genome-wide association study data with epigenetic...
This $2,234,905 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research to understand the underlying mechanisms responsible for cognitive fluctuations in Lewy body disorders (LBD). The University of Iowa, the grant recipient, will use mouse models to evaluate how the buildup of alpha-synuclein protein differentially...
This $682,493 federal Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to elucidate the role of aberrant histone acetylation in the pathogenesis of Parkinson's disease, Lewy body dementia, and related synucleinopathies. The research team at Albert Einstein College of Medicine in Bronx, NY is employing human pluripotent stem...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $231,826 to Duquesne University to conduct research on Lewy body disorders. The research aims to understand the role of microglia/macrophages in the progression of alpha-synuclein aggregation and related neuropathology in an experimental model of Lewy body disease. Key...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is focused on investigating the cellular and molecular mechanisms underlying levodopa-induced dyskinesia (LID) in Parkinson's disease. The $350,036 award to the University of Alabama at Birmingham aims to characterize the unique transcriptional, physical, and physiological changes...