The National Institute of Nursing Research (NINR) awarded a $1,571,724 Project Grant under the Nursing Research program (CFDA 93.361) to Mayo Clinic to provide pulmonary rehabilitation and health coaching for rural patients with chronic obstructive pulmonary disease (COPD). The 5-year project aims to increase access to critical pulmonary rehabilitation services and improve physical and emotional quality of life for this underserved population. The intervention will deliver home-based pulmonary...
This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $1,107,276 to Lasarrus Clinic And Research Center Inc. to develop a mobile health system for remote monitoring of patients with Chronic Obstructive Pulmonary Disease (COPD). The project aims to enhance patient adherence to remote monitoring and early symptom recognition, in order to reduce COPD readmissions and healthcare costs. The system utilizes a wearable...
This federal Project Grant award of $725,088 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) aims to optimize the effectiveness and implementation of COPD self-management treatment. The primary goal is to conduct a factorial optimization trial among 448 individuals with COPD to evaluate the impacts of treatment components including self-management education, physical activity, and inhaler training on respiratory-related hospitalizations and...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $190,825 to investigate right ventricular (RV) function and exercise training for patients with chronic obstructive pulmonary disease (COPD). The research aims to identify patterns of RV contractile response to aerobic exercise and assess the feasibility of an exercise training intervention targeted to improve RV function. The...
This federal Project Grant award of $233,250 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) will fund a research study at the University of Iowa to characterize changes in airway and chest wall deformation between inspiratory and expiratory lung volumes in patients with chronic obstructive pulmonary disease (COPD). The study will leverage established datasets from nationwide longitudinal lung studies to develop normative models of airway and...
The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research (CFDA 93.837) program, awarded a $310,948 Project Grant to Minnesota Healthsolutions Corporation, a for-profit woman-owned small business, on September 15, 2023. The grant funds the development of an adaptable platform to support patients with behavior change interventions aimed at improving adherence to treatment and prevention for multiple chronic diseases. The platform will utilize remote...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) will provide $374,592 to the University of Rochester to support Dr. Lachant's research on an electronically-delivered rehabilitation program for patients hospitalized with acute pulmonary embolism. The goal is to evaluate whether a prescriptive exercise program can reduce post-pulmonary embolism syndrome by addressing deconditioning and anxiety. The study will...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under CFDA Program 93.837 - Cardiovascular Diseases Research will provide $116,625 to The University of Iowa to characterize clinically relevant phenotypes related to osteoporosis and sarcopenia in chronic obstructive pulmonary disease (COPD). The project aims to develop normative models of phenotypic aging, automated CT-based measures of bone, muscle, and lung diaphragmatic surface deformation, and...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $445,648 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Mayo Clinic for the "Translational Training in Respiratory Disease and Repair" project. This 5-year program (1/1/2025 - 12/31/2029) will train 5 postdoctoral trainees in basic, translational, and clinical research to advance respiratory medicine and restore respiratory function. The interdisciplinary program leverages expertise...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $762,867 to The Johns Hopkins University to conduct research on the role of the protein cofilin-1 in maintaining mitochondrial function and airway epithelial health. The research aims to 1) determine how the loss of cofilin-1 impacts mitochondrial dynamics, 2) assess the effects of cofilin-1 loss on mitophagy and mitochondrial...