Project Grant R56HD096737
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865), aims to investigate the potential impacts of postpartum exogenous oxytocin administration on maternal-neonatal oxytocin signaling and behavior in a translational rat model. The $427,625 award, granted on August 6, 2025, will fund research conducted by The Washington University to: 1) quantify...
- The National Institute of Child Health and Human Development (NICHD) awarded a $624,998 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Giner Inc. of Auburndale, Massachusetts. The award will fund the development and validation of an electrochemical assay and point-of-care instrument for highly sensitive, near-real-time perinatal monitoring of oxytocin levels. Oxytocin is a critical neuropeptide hormone for facilitating childbirth and...
- This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), CFDA 93.865 Child Health and Human Development Extramural Research program, provides $235,803 to Texas A&M Engineering Experiment Station (Tees) to bioengineer an in vitro 3D human myometrium model. The goal is to directly evaluate the kinetics (amplitude, velocity, and duration) of myometrial smooth muscle contraction in response to oxytocin, a synthetic hormone...
- The federal Project Grant award, valued at $743,287.00 and funded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a multi-disciplinary research effort to uncover novel insights into endocervical mucus secretion. The primary goal of this 5-year project, which began on May 20, 2025, is to identify the cells and pathways that influence mucus changes in response to hormonal...
- This Project Grant award, totaling $652,723.00, was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports preclinical research to evaluate the efficacy of an innovative in utero pharmacological approach using anti-myostatin monoclonal antibody therapy to improve bone and muscle strength in offspring with Osteogenesis Imperfecta (OI), a...
- This $760,950 Project Grant was awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research Program (CFDA 93.865). The grant supports research at the University of Michigan to characterize how antibody fragments can modulate the signaling of G-protein coupled receptors (GPCRs), such as the oxytocin receptor and angiotensin II type I receptor, which are important in maternal and fetal health during pregnancy. The...
- The National Institute of Child Health and Human Development (NICHD) awarded a $427,625 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Washington University in St. Louis, Missouri. The grant aims to provide a mechanistic understanding of how maternal obesity affects uterine contractility and energy metabolism during labor and parturition. The researchers will use a mouse model of diet-induced obesity to investigate the impacts of excess fatty acids...
- This Project Grant award, valued at $643,049.00, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports the development of a physiomimetic model of endometrioma, a type of endometriotic lesion, to study processes driving lesion initiation, ovarian stroma invasion, and persistence in a chronic inflammatory environment. The research aims to uncover...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $1,603,292.00 to the University of Virginia to study the impact of cesarean section delivery on the maternal brain's epigenetic and transcriptional state, particularly as it relates to the oxytocin system and risk of postpartum depression. The project aims to investigate how...
- This Project Grant award of $765,571 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research on placental fatty acid metabolism in gestational diabetes mellitus (GDM). The project aims to investigate sexual dimorphism in placental function and its role in adverse pregnancy outcomes associated with GDM, with a focus on understanding the effects of GDM...
This Project Grant award of $999,593.00 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to improve understanding of oxytocin receptor (OXTR) function and dynamics. The key objectives are to quantitatively define the trafficking of the OXTR in uterine smooth muscle (myometrial) cells, including membrane insertion, internalization, and recycling. This research is intended to help address the unpredictability in individual responses to oxytocin, which is used to induce or augment labor in about half of all births in the United States. The award was made on September 1, 2025, with an ultimate completion date of August 31, 2027. The research will be conducted by The Washington University, a leading academic research institution with extensive expertise in federal grant execution across diverse scientific domains.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $999.6k | 8/29/25 |