This $314,827 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will fund a randomized clinical trial to evaluate a modified vertical sleeve gastrectomy (MVSG) procedure compared to the conventional vertical sleeve gastrectomy (CVSG) for patients with obesity and gastroesophageal reflux disease (GERD). The study aims to determine if the MVSG technique...
This Project Grant award of $964,718 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research will fund research at Northwestern University to develop and validate a "Virtual Esophagus" (VESOPHAGUS) simulation model. The goal is to leverage this model to define the physiomechanical factors driving poor outcomes in patients with achalasia and gastroesophageal reflux disease (GERD),...
This Cooperative Agreement award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $451,297 to the University of Louisville to investigate the use of Gastric Electrical Stimulation (GES) for treating abdominal pain in patients with gastroparesis. The project aims to evaluate two novel parameter settings for the Enterra GES device - one derived from preclinical studies (PP) and one modified from the...
This Cooperative Agreement award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund a $389,578 multi-center clinical research project focused on improving the treatment of achalasia, a rare esophageal motility disorder. The project, titled "Precision Medicine in Achalasia - PREMEDIA", aims to test an innovative, tailored approach to per-oral endoscopic...
This Project Grant awarded by the National Cancer Institute (NCI), under the federal Cancer Detection and Diagnosis Research program (CFDA 93.394), provides $399,789 to Ergami Endoscopy, Inc. to develop an automated robotic flexible overtube device capable of blind insertion during colonoscopy procedures. The device aims to reduce physician injuries, improve productivity, and decrease patient pain/sedation requirements for the over 16 million colonoscopies performed annually in the U.S. Key...
This $1 million cooperative agreement from the National Science Foundation will support Reflodx, Inc. in developing a novel, noninvasive device to detect and characterize the presence or absence of a bolus in the upper esophagus. Under the NSF Technology, Innovation, and Partnerships program, Reflodx will continue work on a patented pulse-echo ultrasound technology using proprietary algorithms to create an acoustic signature that can differentiate a bolus in the esophagus. Over the two-year...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to develop and test a drug-eluting chest tube to locally manage the pain associated with its use in cardiothoracic surgeries. The $275,752 award supports two key objectives: 1) completing GMP/GLP studies on the drug release kinetics, stability, and manufacturing of the drug-releasing chest tube; and 2) evaluating the mechanical...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $298,368 to Link Medical LLC to develop a novel device for treating mitral valve regurgitation. The funded project aims to optimize the device design and procedure through bench testing, followed by in vivo feasibility studies. The goal is to create a simpler, more robust, and more effective solution than existing technologies for...
This $274,547 Project Grant awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program aims to develop a novel Aneurysm Sealing Device (ASD) for endovascular treatment of Abdominal Aortic Aneurysms (AAA). The project seeks to create a device that can completely seal the aneurysm sac, reducing the risk of post-procedure complications and the need for repeat interventions. Key objectives include validating the device's adaptability...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $324,678 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Lumina Medical LLC, a for-profit limited liability company located in Culver City, California. The grant supports the development of a motorized, girth-adjustable anal dilator device designed to improve patient adherence to anal dilation treatments for conditions such as anismus and anal...