This Project Grant award from the National Cancer Institute (NCI), under the Cancer Detection and Diagnosis Research program (CFDA 93.394), will support the development and clinical validation of an Optical Coherence Tomography (OCT) system and two specialized OCT imaging probes to enhance colorectal cancer screening. The $1,471,777 award to The General Hospital Corporation (doing business as Massachusetts General Hospital) aims to create an OCT system that can obtain 3D microscopic images of...
This Project Grant award from the National Cancer Institute (NCI), under the Federal Assistance Listings program CFDA 93.395 Cancer Treatment Research, provides $406,500.00 to support the development of a novel, low-cost, single-use trans-nasal cryotherapy device for esophageal cancer treatment in low-resource settings. The project aims to design and validate a functional prototype of this first-of-its-kind device, which would enable unsedated cryoablation procedures to be administered through...
This Project Grant award from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395) provides $838,162 to Averto Medical Inc. to conduct a clinical trial of the Coloseal ICD System, a novel medical device designed to eliminate the need for temporary ostomy surgeries in rectal cancer patients. The Coloseal ICD System is a minimally-invasive technology that can safely replace the function of temporary ostomies, which are commonly required for rectal cancer...
This federal Project Grant award, totaling $592,866, was provided by the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) to Georgia Tech Research Corporation to develop ingestible nanosensors for the breath-based detection of colorectal cancer. The key objectives of this 5-year project are to engineer ingestible nanosensors that can sense specific enzymes in the intestinal tract associated with colorectal cancer development and release volatile reporter...
This Project Grant award, titled "Optical Hyperspectral Nanoscale Chromatin Analysis for Colon Cancer Risk-Stratification", is funded by the National Cancer Institute (NCI) under CFDA 93.394 Cancer Detection and Diagnosis Research program. The $670,534 award to Northwestern University aims to develop a screening test to identify patients who harbor advanced adenomas and would benefit from colonoscopy, a crucial step in preventing colorectal cancer, the second leading cause of cancer...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,990 to Scorpido Photonics aims to develop a prototype endoscope-based diagnostic system for rapid, non-invasive detection of microscopic tumors. The project integrates plasmonic nanobubble sensors into a medical device platform and standard endoscope to enable instant, optical detection of cancerous tissues during lung cancer diagnostic procedures. The key product is a...
The National Cancer Institute awarded a $317,420 Project Grant (CFDA 93.394 - Cancer Detection and Diagnosis Research) to Calla Health Foundation, a for-profit, woman-owned small business, for the development and validation of a patient-ready device called the CallaScope. This innovative technology aims to transform provider-controlled speculum-based imaging in a clinic to a patient-controlled self-imaging procedure at home, enabling increased access to cervical cancer screening, diagnosis,...
The National Cancer Institute (NCI) awarded a $962,560 Project Grant (CFDA 93.394 - Cancer Detection and Diagnosis Research) to Basic Health International Inc., a non-profit organization in Pittsburgh, Pennsylvania. The grant aims to modify and clinically validate the IRISTM device, a handheld thermal ablation device and digital colposcope designed for cervical cancer screening and treatment in low- and middle-income countries (LMIC). The key goals of the project are to: 1) Modify the IRISTM...
This federal Project Grant award of $718,456 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) supports research and development of an AI-powered system for automated analysis of abdominal CT scans to enhance detection and tracking of metastatic colorectal cancer. The key products and services to be delivered include: 1) Creating a large-scale...
This $354,066 federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) will support the development of a smart and connected robotic system for comprehensive diagnosis of abnormal tissues in the abdominal cavity. The award will fund research across three main thrusts: 1) integrating a multimodal instrument with balloon-based ultrasound and Raman spectroscopy capabilities to detect, classify, and stage tissue; 2) developing a tendon-driven continuum...