Project Grant R43GM165201
Award Date 8/13/26
Completion Date 7/31/27
Dollars Obligated $314K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Peoria, IL 61606, USA
Similar Awards
- The National Institute of General Medical Sciences awarded Midwest Bioprocessing Center, Inc. $313,770 on September 1, 2026, under the SBIR program to develop a scalable fermentation system for producing pseudaminic acids and their CMP-activated derivatives. The award supports Phase I research to establish proof-of-concept for cost-effective biosynthetic production of pseudaminic acid compounds—specifically PSE5AC7AC and analogs PSE5AC7HB and PSE5AC7FM in free and CMP-activated forms....
- The National Institute of General Medical Sciences, a component of the National Institutes of Health, awarded The University of Chicago $590,711 in project grant funding on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859). The funding supports development of new synthetic methods to accelerate preparation of diverse analogues for medicinal chemistry studies. Over the five-year performance period ending June 30, 2031, the research addresses carbon-carbon...
- The National Institute of General Medical Sciences awarded The Johns Hopkins University $833,955 on September 10, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to develop tools for mapping the glycan-protein interactome using bioorthogonal chemistry and deep learning. The recipient will synthesize and optimize bifunctional ganglioside probes bearing photoaffinity diazirines and click alkyne tags, deliver these probes to human cancer cell lines to capture...
- The National Institute of General Medical Sciences awarded $338,892 to the University of Illinois on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) for organometallic chemistry research on nickel enzymes. The project focuses on developing catalytic and functional mimics of acetyl-coenzyme A synthase (ACS) and [NiFe] hydrogenase through the design of flexible multidentate ligands with mixed hard/soft donor atoms. The research aims to detect and...
- The National Institute of General Medical Sciences awarded the Trustees of Boston University $437,036 on June 1, 2026, for genomic enzymology research to decipher bacterial membrane-associated glycan assembly under the Biomedical Research and Research Training program (CFDA 93.859). The funded work identifies and assigns functional signatures for substrate specificity in phosphoglycosy transferase and glycosyltransferase enzymes to enable glycan composition inference at the protein sequence...
- The National Institute of General Medical Sciences awarded Proteovista LLC $306,151 on June 2, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop ClusterBuild, a platform for cost-effective synthesis of large biosynthetic gene clusters up to 100 kilobases in size. ClusterBuild combines DNA microarrays with peptide nucleic acid (PNA)-based error correction and isothermal assembly to enable high-fidelity synthesis of biosynthetic gene clusters derived from...
- The National Institute of General Medical Sciences awarded $439,281 to the University of California, San Diego on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop and deliver GLYCOCRAFT.EDU, a modular, experiment-based educational platform for glycoscience training. The platform addresses underrepresentation of glycan research in biomedical education by providing portable, hands-on training kits that enable researchers at all career stages to...
- The National Institute of General Medical Sciences awarded the University of California, Davis $675,667 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop chemoenzymatic strategies for synthesizing glycans and glycoconjugates. The research program focuses on two major directions: developing innovative chemoenzymatic methods for synthesizing complex bacterial surface glycans, including those with multiple polysaccharide repeating units applicable...
- The National Institute of General Medical Sciences awarded the University of Illinois $303,685 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to discover and characterize RIPP biosynthetic enzymes. The work focuses on assigning catalytic function to domains of unknown function (DUFs) encoded in microbial genomes, particularly those involved in ribosomally synthesized and posttranslationally modified peptides (RIPPs) biosynthesis. The research...
- The National Institute of General Medical Sciences awarded the University of Illinois $1,385,652 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop in vivo metabolic tagging and targeting of long-circulating red blood cell biomembranes. The project aims to create a platform technology for metabolic tagging of red blood cell (RBC) membranes using unnatural sugars and subsequent targeting of molecular imaging and therapeutic cargo via click...