Project Grant R43GM160998
Award Date
5/1/25
Completion Date
4/30/26
Dollars Obligated
$345K
Federal Agency
National Institute of General Medical Sciences
Awardee
Kasa Bio, L.L.C. (CHX9LW14AXB4)
Federal Grant Program
93.859
Assistance Type
Project Grant
Place of Performance
Georgia, USA
Similar Awards
The National Institute of General Medical Sciences (NIGMS) awarded a Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Molecular Instruments, Inc., a for-profit manufacturer of scientific instruments, in the amount of $905,853. The funding will support the company's research and development of advanced technologies for automated, ultrasensitive, and multiplex imaging of RNA and proteins in biological samples. Specifically, the project aims to engineer...
This Project Grant award, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop a novel enzyme-free, label-free quantitative microarray technology to profile microRNA (miRNA) sequences with high sensitivity. The $432,834 award to the Board of Regents of the University of Nebraska will fund research to design a "perfect switch" binary probe that can quantify a mixture of up to 25...
This $349,816 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) aims to develop a prototype instrument, software, and consumable for non-invasive identification, tagging, and downstream characterization of live cells. The product will enable researchers to study clinically relevant cell-cell interactions, which drive many challenging diseases like cancer, autoimmunity, and neurological disorders....
This National Science Foundation (NSF) Project Grant award for $380,074, awarded on September 1, 2024, aims to develop a platform for instrument-free, easy-to-interpret quantitative analysis of molecular biomarkers. The project will produce a general methodology adaptable to a range of molecular targets, including potential new agents. The key products to be delivered include: A "yes/no" output for quantitative measurement, enabled through stoichiometry and negative cooperativity-based...
This $440,287 federal Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) aims to establish a simplified and accessible procedure for simultaneous extraction of DNA, RNA, and protein from tumor touch imprints. The objective is to democratize cancer biobanking by enabling smaller and lower-resource institutes to participate, addressing the current underrepresentation of samples from non-white patient populations. The project will optimize...
This $274,594 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports research and development of an innovative technology for cancer diagnosis and treatment. The project aims to improve molecular profiling and clinical laboratory testing of cancer samples by optimizing microdissection techniques. The research will focus on modeling and optimizing the opto-thermal-mechanical interactions involved in microdissection to...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) is funding the development of a system to protect and concentrate large DNA molecules for genome analysis at the University of Nebraska. The $394,857 award, active from August 6, 2024 to July 31, 2027, aims to create an innovative system using 3D printing, a DNA "roadblock," and an inverted insert to protect and concentrate DNA...
This Project Grant award from the National Human Genome Research Institute (NHGRI), under the Human Genome Research Federal Grant Program (CFDA 93.172), supports the development of an innovative platform called CytopeDrop by Survey Genomics, Inc. CytopeDrop enables high-throughput, spatially-resolved multiomics analysis at the single-cell level, integrating measurements of mRNA abundance, protein expression, and cell location. The $1,887,931 award, with a project period from September 2024 to...
This $448,150 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop a DNA-based toolbox for the rapid and precise modulation of cell membrane protein-protein interactions (PPIs). The goal is to establish a modular approach using antibodies and aptamers to enable targeted DNA barcoding of cell membrane proteins, particularly receptor tyrosine kinases. This will allow for the controlled stabilization of specific PPI pairs on living...
The federal Project Grant award R01EB037031, funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will develop living biosensors for detecting and analyzing DNA at the single-base level without requiring sample purification or specialized equipment. The $257,807 award, with a project period from April 2025 to March 2029, aims to create a hybrid living...