The National Institute of General Medical Sciences (NIGMS) awarded a $333,048 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Imagen Bioworks Inc. in Houston, TX. The goal of this 1-year project is to develop a versatile 2-photon microscopy platform, dubbed 2P-SPOTLIGHT, to isolate individual cells from 3D tissue samples and 3D cell cultures based on their spatial and temporal properties. This will enable researchers to conduct downstream multi-omics...
The National Institute of General Medical Sciences (NIGMS) awarded a $917,454 Project Grant under CFDA 93.859, Biomedical Research and Research Training, to Integral Molecular Inc. The grant supports the development of a novel Membrane Proteome Array (MPA) technology for specificity screening and profiling of biotherapeutics like monoclonal antibodies and CAR-T cell therapies. The MPA represents 93% of the human extracellular proteome expressed in native conformation, providing a more...
The National Institute of General Medical Sciences (NIGMS) awarded a $314,363 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Tango Biosciences Inc. in Chicago, Illinois. The grant supports the development of the Avidimer Platform, a novel phage display-based technology to create affinity reagents and enable high-throughput screening for identifying "molecular glues" - small molecules or biologics that induce proximity between two protein...
The National Institute of General Medical Sciences (NIGMS) awarded a $999,998 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Kinetic River Corp. of Mountain View, CA. The grant supports the development and refinement of Kinetic River's ARNO flow cytometer, which eliminates the need for spectral compensation in advanced flow cytometry analysis. Specifically, the funding will enable Kinetic River to: Reduce the cost of the ARNO's data acquisition...
The National Institute of General Medical Sciences (NIGMS) awarded a $218,622 Project Grant to Vitan-Biotech LLC on September 22, 2023 under the Biomedical Research and Research Training program (CFDA 93.859). The grant will fund the development of an integrated pipeline to rapidly discover and characterize selective, high-affinity nanobodies against defined G protein-coupled receptors (GPCRs) that are important for neurological disorders like schizophrenia, pain, Parkinson's, Alzheimer's, and...
The National Institute of General Medical Sciences (NIGMS) awarded a $330,076 Project Grant to Trestle Optics LLC under the Biomedical Research and Research Training (CFDA 93.859) federal grant program. The grant funding will support the development of a photothermal microscopy platform that can non-destructively profile metabolites in individual cells. The project aims to integrate photothermal microscopy with spatial light interference imaging to create a system capable of real-time,...
The National Institute of General Medical Sciences (NIGMS) awarded a $675,609 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) federal grant program to Ometa Labs LLC, a minority-owned small business based in Carlsbad, CA. The grant supports the development of a bioinformatics platform for large-scale untargeted metabolomics analysis. The project will run from August 1, 2025 to July 31, 2027, with the goal of advancing fundamental scientific understanding,...
The National Institute of General Medical Sciences (NIGMS) awarded a $324,239 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Ora Biomedical, Inc., a biotechnology company in Seattle, WA. The purpose of this Phase I Small Business Innovation Research (SBIR) grant is to develop "ELEGANTRY", a software and hardware infrastructure to improve rigor and reproducibility in invertebrate research using the model organism Caenorhabditis elegans (C....
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) is funding the development of a Spotting-Free Nano-Oscillator Array (SFNOA) technology by Biosensing Instrument Inc. The SFNOA system aims to enable high-throughput, label-free quantification of ligand binding kinetics to transmembrane proteins in their native states. The $349,566 award, effective from April 2, 2025 to March 31, 2026,...
The National Institute of General Medical Sciences (NIGMS) awarded a $298,530 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Epigenter, LLC in Providence, RI. The goal of this 1-year award, effective July 1, 2025, is to develop and characterize "self-delivering" epigenetic editor proteins that can modulate gene expression by targeted DNA demethylation, without requiring genetic transduction. The project will compare two different protein...