Project Grant R43EB026411

Cooperative Agreement Award Summary The University of California, San Diego received an $18.3 million Cooperative Agreement award from the Advanced Research Projects Agency for Health (ARPA-H, CFDA 93.384) on September 25, 2025, to develop a scalable, patient-specific bioprinted liver using induced pluripotent stem cells (iPSCs). The project, which extends through September 24, 2028, aims to create functional liver tissue tailored to individual patient anatomy and physiology without requiring...

Carnegie Mellon University received an $18.1 million Cooperative Agreement from the Advanced Research Projects Agency for Health (ARPA-H, CFDA 93.384) awarded September 26, 2025, with completion scheduled for September 25, 2028. The LIVE (Liver Immunocompetent Volumetric Engineering) project aims to develop three-dimensional bioprinted liver tissue constructs that eliminate the need for systemic immunosuppression and organ transplantation. The initiative unites world-leading experts in 3D...

Federal Grant Award Summary Bioprinting Laboratories Inc. received a $306,872 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective July 8, 2025, with completion by October 31, 2026. The company will develop a high-throughput testing platform utilizing genetically engineered induced pluripotent stem cells (iPSCs) differentiated into brain organoids to assess developmental neurotoxicity (DNT) in...

This federal Project Grant award of $460,500 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) is aimed at developing novel bioprinting methodologies for the production of human stem cell-based organoids. The key objectives are to: 1) Create a customized bioink formulation using proteins, polysaccharides, and functionalized nanoparticles to foster the...

This $500,000 Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program aims to develop a novel human stem cell-based microfluidic developmental toxicology platform. The University of Michigan will receive funding from September 2022 to August 2024 to conduct technological development of a repeatable, controllable, high-throughput microfluidic system for generating three-dimensional multicellular organoid models for toxicity testing. The platform seeks...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) grant, awarded to Tissueform, Inc., a for-profit woman-owned small business in Boulder, Colorado, aims to develop a library of human-based bioinks for 3D bioprinting applications. The $274,822 award, with a performance period from September 2024 to August 2025, will focus on creating granulated bioinks for tissues such as cartilage, bone, skin, liver,...

This Project Grant award from the National Institutes of Health (NIH) Research Infrastructure Programs (CFDA 93.351) provides $270,428 to TEO Therapeutics Incorporated, a small disadvantaged business, to develop a biomimetic platform for more efficient pharmaceutical drug development in oncology. The key products and services to be delivered include: Refining and testing a proof-of-concept hardware product line for a Shell-Free Quail Xenograft Assay, optimizing throughput and assessing...

Federal Cooperative Agreement Summary Award Overview Harvard College received a $17.8 million Cooperative Agreement from the Advanced Research Projects Agency for Health (ARPA-H, CFDA 93.384) awarded September 26, 2025, with completion targeted for September 25, 2028. The award funds development of an off-the-shelf engineered liver tissue product to address the critical shortage of donor organs for patients with liver failure. The project leverages induced pluripotent stem cell (iPSC)...

This $250,000 National Science Foundation Technology, Innovation, and Partnerships Project Grant supports the development of artificial substrates for growing human stem cells suitable for clinical applications at Oakland University from March 2023 to February 2025. The goal is to accelerate the potential benefits of using human pluripotent stem cells and their derivatives for treating and curing diseases by producing a synthetic substrate that supports growth of human pluripotent stem cells...

The federal Project Grant award of $350,000 was provided by the National Center for Advancing Translational Sciences (NCATS), under the CFDA Program 93.350, to Vivosphere LLC in Auburn, AL. The funding will support the development of "Vivospheres", which are tissue-engineered spheroidal models for high-throughput screening. The project aims to establish Vivospheres as a more consistent and flexible 3D cell culture system compared to traditional self-aggregation methods, enabling...