Project Grant R43AT013358
- The National Center for Complementary and Integrative Health (NCCIH), under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), awarded a $1,262,764 project grant to the Sloan-Kettering Institute for Cancer Research. The grant is intended to support research on the use of isoquercetin, a flavonoid compound, as an inhibitor of protein disulfide isomerase (PDI) to develop an antithrombotic agent for cancer patients at high risk of venous thromboembolism. The...
- This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the federal Research and Training in Complementary and Integrative Health program (CFDA 93.213), provides $306,793 to Vivoverse, LLC, a woman-owned small business in Austin, Texas, to develop an automated high-throughput screening platform using the C. elegans model organism. The project aims to create imaging-based assays to assess the effects of natural products, including plant extracts...
- The National Center for Complementary and Integrative Health (NCCIH) awarded a $466,125 Project Grant under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to Weill Medical College of Cornell University. The project, titled "PUFA Partitioning into Condensates as a New Mechanism for Gene Regulation," aims to explore a new explanation for why specific polyunsaturated fatty acids (PUFAs) regulate PPARG-mediated transcription initiation more than...
- This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH) under CFDA 93.213 - Research and Training in Complementary and Integrative Health provides $451,000.00 in funding to The Trustees of Princeton University from September 2024 to August 2026. The objective is to characterize the secondary metabolomes of three Corynebacterial strains, including uncovering the small molecule products they use to compete with other microbes and interact with host cells....
- This federal Project Grant award of $295,780.00, funded by the National Center for Complementary and Integrative Health (NCCIH) under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), supports the development of a high-throughput in vivo screening platform to identify novel probiotic and postbiotic bacterial strains. The awardee, Nemalife Inc., will leverage the nematode Caenorhabditis elegans as a model organism to rapidly screen and characterize bacterial...
- This $350,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of an integrated workflow that combines computation and experimentation to efficiently expand a metabolomics-enabled drug discovery (MetD4) dataset. The primary focus is on developing neural network models to enable efficient metabolomic characterization of compound libraries, which will aid in...
- This $222,412 Project Grant award from the National Center for Complementary and Integrative Health (NCCIH) under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) will fund a 2-year research project at the University of South Florida to study the natural products derived from archived coral specimens held in natural history museum collections. The project aims to leverage recent advancements in analytical instrumentation and bioinformatic platforms to...
- The National Center for Complementary and Integrative Health (NCCIH), part of the U.S. Department of Health and Human Services, awarded a $293,920 Project Grant under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to SocialRx Inc. (dba Art Pharmacy). The grant funds the design, development, and beta testing of a minimum viable product (MVP) for a digital companion app that will provide personalized recommendations and support for youth to access...
- This federal Project Grant award, totaling $416,134, was provided by the National Center for Complementary and Integrative Health (NCCIH) under the Research and Training in Complementary and Integrative Health program (CFDA 93.213). The grant supports the development of a botanical drug product called ZINDOL, which is based on ginger, for the treatment of chemotherapy-induced nausea and vomiting (CINV). The project aims to develop and manufacture a highly purified and standardized ginger-based...
- This federal Project Grant award of $241,102, provided by the National Center for Complementary and Integrative Health (NCCIH) under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), supports the development of an artificial intelligence-based recommendation engine for Art Pharmacy's social prescribing platform. Art Pharmacy is an arts-based social prescribing company that provides personalized arts prescriptions to help patients at risk of or...
The National Center for Complementary and Integrative Health (NCCIH), part of the U.S. Department of Health and Human Services, awarded a $306,872 Project Grant under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to Evoquant LLC. The funding supports the development of the "BioPredictor" platform, an innovative artificial intelligence and multi-omics system designed to enhance natural product drug discovery and target selection. The project aims to: 1) refine and scale the BioPredictor platform using advanced AI/ML algorithms; 2) prioritize biosynthetic gene clusters and microbial strains with potential to yield novel therapeutics; and 3) conduct assays to validate the platform's predictions and therapeutic development applications. This project seeks to accelerate the discovery and application of novel natural product-derived therapeutics, particularly for rare diseases and cancers, by improving the prediction of natural product bioactivity.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $306.9k | 9/3/25 |