This federal Project Grant award of $295,780.00, funded by the National Center for Complementary and Integrative Health (NCCIH) under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), supports the development of a high-throughput in vivo screening platform to identify novel probiotic and postbiotic bacterial strains. The awardee, Nemalife Inc., will leverage the nematode Caenorhabditis elegans as a model organism to rapidly screen and characterize bacterial isolates from the human gut microbiome. The goal is to establish a cost-effective, scalable screening pipeline to discover and translate new probiotics and postbiotics with therapeutic potential for conditions like obesity, sarcopenia, and neurodegenerative diseases associated with gut dysbiosis. The project will build a database of beneficial microbiome species, functionally characterize their health impacts, and elucidate the underlying mechanisms of action using transcriptomics. This research aims to accelerate the identification and commercialization of novel microbial-based interventions to address various human health disorders.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $295.8k | 9/17/24 |