Project Grant R43AR083301
Award Date
9/20/23
Completion Date
8/31/24
Dollars Obligated
$302K
Federal Grant Program
93.846
Assistance Type
Project Grant
Place of Performance
Charleston, SC 29406, USA
Similar Awards
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $241,778 to Polymerix Technologies LLC to develop an improved process for manufacturing crosslinked ultra-high molecular weight polyethylene (UHMWPE) components for joint replacement implants. The key objectives are to optimize a pressure-quenching process to enhance the mechanical...
This Project Grant award, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will support the development of pre-operative planning software to guide surgical treatment of patellar instability. The $292,954 award to Ortho Haus, LLC will fund the generation of data required to develop a computational model that can quantify an individual patient's patellar joint...
This federal Project Grant award of $651,662 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports research to identify key downstream mediators and potential therapeutic targets regulated by the TGF-β pathway in articular cartilage and osteoarthritis (OA) pathogenesis. The research aims to establish the transcription factor NFIA as a crucial regulator of lipid...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is developing the X-Visual, a sensor to track fracture healing in cannulated screws used for hip fracture fixation. The $299,999 award to Aravis Biotech LLC will cover the design, computational modeling, and initial testing of this innovative device that can non-invasively measure screw bending...
This Project Grant award with Federal Grant ID R21AR082992 was awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The $752,620 grant supports the development of injectable, cell-adhesive alginate hydrogels containing insulin-like growth factor 1 (IGF-1) mimicking peptides. The goal is to enhance the therapeutic potential of mesenchymal stem cells (MSCs) for repairing...
This $295,481 Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) aims to develop and validate a novel multifunctional colloidal scaffold called "MuscleInk" for the treatment of volumetric muscle loss (VML). MuscleInk is a gelatin-methacryloyl-based porous scaffold that can be crosslinked in situ and is impregnated with insulin-like growth...
This $504,965 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports the late-stage development of a sustained-release relaxin therapeutic for treating shoulder contracture, also known as "arthrofibrosis." The awardee, Ortholevo, Inc., a for-profit biotechnology company, aims to advance this novel treatment approach through several key...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $393,412 to Vanderbilt University to develop engineered cell-based therapies to treat osteoarthritis. The project aims to leverage synthetic biology approaches to create programmable cells that can detect and respond to articular cartilage damage, triggering the upregulation of genes that...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), with CFDA number 93.846 Arthritis, Musculoskeletal and Skin Diseases Research, will provide $456,808 to the Buck Institute for Research on Aging to develop innovative mass spectrometry imaging (MSI) technologies for spatially visualizing proteins and glycans in joint tissues. The goal is to advance the understanding of disease progression in osteoarthritis and meniscal...
This Project Grant award of $680,325 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research aimed at understanding the critical mechanisms of collagen proteostasis and assessing the therapeutic potential of proteostasis network-targeted interventions for the treatment of collagenopathies. The key products and services to be delivered under this 5-year award...