Project Grant R01AR082995
Award Date
9/4/24
Completion Date
8/31/29
Dollars Obligated
$680K
Federal Grant Program
93.846
Assistance Type
Project Grant
Place of Performance
Cambridge, MA 02139, USA
Similar Awards
The Massachusetts Institute of Technology (MIT) has been awarded a $225,623 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant will support research to elucidate the critical mechanisms of intracellular collagen folding and quality control, with the goal of identifying new therapeutic targets for treating collagen-related diseases, known as...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $151,471 to the University of California, Davis to investigate the use of collagenase to target collagen architecture in fibrotic skeletal muscle. The goal is to reduce muscle stiffness and promote tissue regeneration, with a focus on the extracellular matrix changes seen in Duchenne...
This $456,808 federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is supporting the development of innovative mass spectrometry imaging (MSI) technologies to spatially visualize proteins and glycans in musculoskeletal tissues. The primary awardee, the Buck Institute for Research on Aging, is collaborating with researchers at the University of...
This $863,697 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences will support Provenance Group Inc.'s efforts to efficiently synthesize full-length human Type I collagen with appropriate post-translational modifications at high yields. The company will demonstrate that the recombinant collagen resembles its native counterpart and generate highly productive strains expressing full-length human Type I collagen showing appropriate prolyl...
This federal Project Grant award, valued at $198,170, was issued on July 1, 2024 by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant supports research by Harvard University to investigate the role of the tetraspanin CD151 and its interaction with the integrin α3β1 (ITGA3β1) in regulating basement membrane adhesion and signaling, which is critical for maintaining the...
The federal Project Grant award in the amount of $296,536.00 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports research at The Leland Stanford Junior University (Stanford University) to explore how mechanical loading enhances cartilage formation by chondrocytes in viscoelastic extracellular matrices (ECMs). The project aims to establish a detailed biophysical and...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) has awarded Collamedix Inc. a $300,000 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to establish the feasibility of their "CollaLink" collagen-based scaffold for augmenting primary repair of anterior cruciate ligament (ACL) mid-substance tears. The project aims to demonstrate that the CollaLink scaffold, when placed around an ACL tear, can provide a...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded Panorama Research Incorporated, doing business as Panorama Research Inc., a $275,765 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to develop an antibody-based therapy for reducing scarring and fibrosis following joint surgeries. The project aims to improve the delivery and tissue residence of a lead humanized antibody that inhibits collagen fibril formation, thereby...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $483,070 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to the University of Missouri at Kansas City (UMKC) to conduct research on the dynamics of bone extracellular matrix (ECM) assembly and resorption. The research aims to determine how osteogenic cellular dynamics, differentiation, and cell fate are integrated with collagen assembly and mineralization dynamics, as...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846), is providing $359,133 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to generate new genetic tools for advancing tendon and musculoskeletal research. The grant aims to develop constitutive and inducible FLP alleles that can be used with...