Project Grant R35GM166073
- The National Institute of Allergy and Infectious Diseases awarded Georgia TECH Research Corp $152,600 on December 9, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate how Blastocystis, the most prevalent protist in the human gut microbiome, shapes gut ecosystem function and community structure. The research comprises three aims. Aim 1 examines how Blastocystis metabolizes dietary lipids through biochemical assays, microscopy-based trafficking analysis,...
- The National Institute of General Medical Sciences awarded Georgia TECH Research Corp $421,857 under the Biomedical Research and Research Training program (CFDA 93.859) on August 1, 2026. The award funds development of quantum and nanosensing technologies combined with artificial intelligence to investigate autophagic pathways and lysosomal dysregulation in living systems. The research employs precision synthetic chemistry, nanoscale engineering, spectroscopy, and machine learning to monitor...
- The National Institute of General Medical Sciences awarded Georgia TECH Research Corp $432,850 on June 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct computational research on protein dynamics and allostery in biomedically important enzymes. The work uses biomolecular simulations to explore conformational dynamics, allosteric regulation, and catalytic function in three enzyme systems: PRIA and TRPC (central to tryptophan biosynthesis and potential...
- The National Institute of General Medical Sciences awarded Georgia TECH Research Corp $382,507 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support predator-prey dynamics research in a complex animal microbiome led by Dr. Lauren Speare. The research investigates microbial predator-prey interactions and their consequences for animal hosts using a tripartite system comprising the obligate predatory bacterium Halobacteriovorax marinus, the marine...
- The National Institute of General Medical Sciences (NIGMS) awarded a $1,338,750 Project Grant to Yale University to conduct research on how gut bacteria can influence host feeding behavior and microbiome assembly using the roundworm Caenorhabditis elegans as a model system. The project aims to develop tools and assays to study the molecular mechanisms by which gut microbes can manipulate host feeding decisions, with the goal of gaining insights that may apply to other host-microbe systems. Key...
- The National Science Foundation Division of Integrative Organismal Systems awarded $240,063 to Georgia Tech Research Corporation under a Project Grant titled "COLLABORATIVE RESEARCH: RUI: IMPLICATIONS OF BACTERIALLY DRIVEN CROSS-KINGDOM CHEMICAL INTERACTIONS." The grant period runs from May 15, 2021 through April 30, 2024. The funding supports research into major problems confronting the nation under the Biological Sciences program (CFDA 47.074). Specifically, the grant aims to...
- The National Institute of General Medical Sciences awarded the University of Chicago $451,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct systematic interrogation of diet as a mechanism to shape microbial community configuration and metabolism. The research examines how dietary macronutrients drive growth of specific microbial clades within a complex but defined human microbiome (HCOM2), utilizing in vitro analysis across a panel of...
- This Project Grant award from the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074), provides $833,999.00 to Georgia Tech Research Corporation (Georgia TECH) to investigate how defined microbiomes respond to viruses over short and long timescales. The project aims to test the hypothesis that robust microbiome functions are promoted by microbial communication systems and costs of virus resistance. This...
- The National Institute of General Medical Sciences awarded Texas State University $401,250 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to study the mechanisms of intergenomic epistasis and environmental context in animal-microbe symbioses. Over the five-year performance period through April 30, 2031, the research will use the Aiptasia anemone and its photosynthetic algal symbiont as a model system to characterize how host and symbiont genotypes...
- The National Institute of General Medical Sciences awarded Yale University $462,114 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate stress response mechanisms in beneficial gut bacteria, specifically how Bacteroides thetaiotaomicron uses carbon starvation as a regulatory signal to promote gut fitness factors. The research spans five years (through May 31, 2031) and focuses on establishing novel biological principles governing...
The National Institute of General Medical Sciences awarded Georgia TECH Research Corp $393,500 on August 24, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate how commensal gut protists shape microbiome community ecology and function. Over five years through April 30, 2031, the Lind Laboratory at Georgia Tech will examine gut protist metabolism, identify nutritional inputs and outputs, annotate metabolic gene function, and determine how protist interactions with other gut microbiota influence microbial community composition and function. The research focuses on Blastocystis, the most prevalent commensal protist in humans, using genomic, transcriptomic, metabolomic, and ecological approaches to establish a mechanistic framework for understanding how commensal eukaryotes influence the gut environment. Work is performed at the Atlanta, Georgia campus. The award is classified as a Project Grant under NIGMS's MIRA (Maximizing Investigators' Research Award) program, which supports investigator-initiated basic research that increases understanding of biological processes underlying disease diagnosis, treatment, and prevention.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $393.5k | 8/24/26 |