Project Grant R35GM166059
- The National Institute of General Medical Sciences awarded $441,375 to The Regents of The University of California, doing business as University of California, Berkeley, on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support research on cell and developmental mechanisms of animal responses to intracellular beneficial microbes. The funded research uses the small anemone Aiptasia as a genetically tractable model organism to study the cell biology...
- The National Institute of General Medical Sciences awarded the University of Texas at Austin $415,574 on July 13, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to fund research on immune recognition and response mechanisms in choanoflagellates. The project establishes choanoflagellates—the closest living relatives of animals—as experimental models for investigating host-pathogen interactions and innate immune response. Research will combine comparative...
- The National Institute of General Medical Sciences awarded Arizona State University $300,000 on August 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate synthetic microbial communities and their ecosystem dynamics. The project develops and characterizes synthetic two-component and higher-order E. coli microbial communities with diverse inter-strain interaction topologies, coupling bacterial toxin-antitoxin systems with quorum sensing to create...
- The National Institute of General Medical Sciences, part of the National Institutes of Health within the Department of Health and Human Services, awarded The University of Texas Southwestern Medical Center $488,525 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859), a Project Grant (R35GM162011). The award funds evolution-guided studies of mitochondrial activities and the host response to infectious agents. The research characterizes newly identified...
- The National Institute of General Medical Sciences (NIGMS), part of the Department of Health and Human Services National Institutes of Health, awarded the University of Texas at Dallas $435,875 on June 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859, Assistance Listing) to investigate how tissue-specific progenitor cell fate is governed by mesenchymal progenitors and sympathetic neurons during adult tissue regeneration. The recipient will use the postnatal mouse...
- The National Institute of General Medical Sciences, part of the Department of Health and Human Services, awarded $467,500 to the California Institute of Technology on May 11, 2026, under the Biomedical Research and Research Training program (CFDA 93.859). The research investigates the evolution of symbiotic relationships between rove beetles (Staphylinidae) and ant colonies, focusing on how free-living beetle species transition into obligate symbionts dependent on host ant colonies. The work...
- The National Institute of General Medical Sciences (NIGMS) awarded the University of Arizona $410,775 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to advance synthetic bacterial adhesion tools and engineer multicellular bacterial consortia for health-relevant applications. The research focuses on developing novel synthetic cell-cell adhesion features through protein engineering, creating new synthetic genetic circuits that enable controlled...
- The National Institute of General Medical Sciences awarded Oklahoma State University $373,960 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support research on genome evolution and design in small, single-stranded DNA phages (Microviridae). The award is structured as a Project Grant with a period of performance running through August 31, 2031. Work is performed in Oklahoma City, Oklahoma. The National Institute of General Medical Sciences...
- The National Institute of General Medical Sciences awarded Icahn School of Medicine at Mount Sinai $420,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop and deploy genetic interaction mapping tools in bacteria. The project will construct a comprehensive genetic interaction network in Escherichia coli by developing a barcoded CRISPR strategy to systematically profile all pairwise genetic interactions (approximately 10 million) and...
- The National Institute of General Medical Sciences awarded Texas A&M Engineering Experiment Station $394,917 on July 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop advanced label-free microscopy methods linking cell structure to mechanobiology. The work focuses on quantitative phase imaging and holotomography as nondestructive, non-contact tools for visualizing cytoskeletal structure and predicting cell viscoelasticity in live, unlabeled cells....
The National Institute of General Medical Sciences awarded Texas State University $401,250 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to study the mechanisms of intergenomic epistasis and environmental context in animal-microbe symbioses. Over the five-year performance period through April 30, 2031, the research will use the Aiptasia anemone and its photosynthetic algal symbiont as a model system to characterize how host and symbiont genotypes interact to affect fitness, and how environmental factors modulate those interactions. The investigator's group will create epistasis panels by manipulating host and symbiont genetic pairings, then apply unbiased omics approaches to identify candidate genes and pathways underlying intergenomic interactions. The work is performed in Texas. The award reflects NIGMS's mission to support basic research that increases understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. The research on animal-microbe associations is intended to inform understanding of microbiome impacts on human health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $401.3k | 7/24/26 |