Project Grant R35GM164231
- The National Institute of General Medical Sciences awarded Arizona State University $363,365 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to advance spin-based quantum sensors for single-cell analysis. The research will develop optically addressable spin-qubit magnetometers to detect biological magnetic fields at the nanoscale, focusing on improving sensor coherence and biocompatibility to enable label-free detection of cellular activities...
- Federal Project Grant Award Summary Arizona State University received a $1,977,264 Project Grant award, effective September 15, 2025, through August 31, 2029, under the National Institute of General Medical Sciences' Biomedical Research and Research Training program (CFDA 93.859). The award funds development of a novel multimodal imaging platform that integrates fluorescence super-resolution and tomographic polarized light imaging technologies to enable cellular and unicellular organism...
- The National Institute of General Medical Sciences awarded Arizona State University $300,000 on August 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate synthetic microbial communities and their ecosystem dynamics. The project develops and characterizes synthetic two-component and higher-order E. coli microbial communities with diverse inter-strain interaction topologies, coupling bacterial toxin-antitoxin systems with quorum sensing to create...
- The National Institute of General Medical Sciences awarded the University of Arizona $1.835 million on May 11, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop an ultra-broadband microscope based on an innovative obscuration-free, off-axis freeform reflective optical architecture. The project addresses fundamental limitations of conventional optical microscopy by designing and optimizing a compact, high-performance reflective microscope capable of...
- The National Institute of General Medical Sciences awarded Arizona State University $378,995 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to decode the toxicity-efficacy paradox in gene and nucleic acid therapies. Over five years through August 31, 2031, the funded research will generate an integrated atlas of escape-induced toxicities using phosphoproteomics, transcriptomics, and mediator profiling to map how endosomal escape location and...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Arizona State University $799,995 on August 1, 2026, under the Biological Sciences program (CFDA 47.074) to establish a quantitative framework for understanding reciprocal interactions between biomolecular condensates and cellular growth. The project will use integrated experimental and computational approaches to determine how cellular growth regulates condensate formation, dissolution, and phase-separation...
- Federal Project Grant Award Summary Arizona State University received a $413,036 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2027. The award supports the development of a novel single-molecule glycosaminoglycan (GAG) sequencing method using fluorophore-labeled lysosomal enzymes. Glycosaminoglycans are large, linear, sulfated...
- The National Institute of Biomedical Imaging and Bioengineering awarded Arizona State University $183,307 on June 3, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a pneumatically controlled radiofrequency coil for multinuclear magnetic resonance imaging and spectroscopy applications at 7 Tesla field strength. The funded research addresses technical challenges in multinuclear MRI and MRS by designing a novel...
- The National Institute of Allergy and Infectious Diseases awarded Arizona State University $405,202 on June 5, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop a general method for converting antibodies into fluorescent sensors of their antigens. The research addresses limitations of existing fluorescently labeled antibody diagnostics, which require extensive experimental manipulation and specialized equipment. The funded work builds on preliminary...
- The National Institute of General Medical Sciences, an operating division of the Department of Health and Human Services National Institutes of Health, awarded Arizona State University $404,180 on July 13, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate how bacterial predation via the type VI secretion system shapes ecological and evolutionary dynamics in microbial communities. The D'Souza Lab will study T6SS-mediated antagonism in two bacterial...
The National Institute of General Medical Sciences awarded Arizona State University $2,081,661 on August 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop plasmonic and evanescent scattering microscopy technologies for label-free functional imaging of single molecular and cellular activities. The recipient will advance optical detection methods that measure intrinsic molecular and cellular optical properties without fluorescent or radioactive labeling. Deliverables include refinement of plasmonic scattering microscopy (PSM) and evanescent scattering microscopy (ESM) to detect single protein molecules and binding events, with applications in quantifying protein binding kinetics in complex media, detecting cell-released proteins, and investigating molecular and cellular activities at single-entity resolution. The work builds on prior NIGMS-funded development of surface plasmon resonance microscopy, plasmonic-based electrochemical impedance microscopy for cellular electrical activity imaging, and mechanically amplified detection of molecular interactions on whole cells. Performance occurs in Tempe, Arizona, with a period of performance from August 10, 2026, through July 31, 2030. Arizona State University's Office of Research and Sponsored Projects Administration (Orspa) serves as the federal research administration function. The parent entity is the Arizona Board of Regents. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.1m | 8/5/26 |