Project Grant R35GM162028
- Federal Grant Award Summary The Washington University received a $912,250 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective May 1, 2025 through March 31, 2030. The award funds basic biomedical research investigating the spatiotemporal regulation of organelle interactions and metabolism, specifically examining how protein networks control lipid droplet growth and degradation. The...
- Federal Project Grant Award Summary The Washington University received a Project Grant award of $427,625 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025, through July 31, 2030. The award supports fundamental research investigating the molecular mechanisms of compound microtubule structure and function within the mammalian centrosome-cilium complex. The research employs advanced...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Washington University a Project Grant totaling $326,550 under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2030. This five-year award supports fundamental research aimed at developing ecological theory and computational methodologies to predict and design microbial ecosystem functions. The research addresses a...
- Federal Project Grant Summary The National Institute of General Medical Sciences (NIGMS) awarded The Washington University a $2.78 million Project Grant (CFDA 93.859: Biomedical Research and Research Training) effective September 1, 2025, through August 31, 2029. This award supports fundamental basic research investigating the role of the ribosome and translation factors in mediating cellular stress signaling. The research focuses on understanding how cells recognize and respond to chemical...
- Federal Project Grant Award Summary The Washington University received a $1.244M Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded April 1, 2026, with completion targeted for March 31, 2030. The award supports development of an integrated software-hardware platform that enables real-time, feedback-based control of mechanical forces on cells and engineered tissues—a capability absent...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Washington University a Project Grant totaling $416,050 under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the metabolic and regulatory mechanisms controlling antibiotic production in filamentous actinobacteria. The award, announced on August 5, 2025, with completion targeted for May 31, 2030, supports fundamental basic research aimed at unlocking the...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Washington University $382,931 under the Biomedical Research and Research Training program (CFDA 93.859) to conduct fundamental research on mitochondrial AAA (ATPase-Associated with diverse cellular Activities) protease specificity and function. The five-year project, which commenced September 1, 2025, and concludes August 31, 2030, will employ an integrated multidisciplinary approach combining...
- Federal Grant Award Summary The Washington University received a $430,000 Project Grant from the National Science Foundation (NSF) Division of Materials Research under the Mathematical and Physical Sciences program (CFDA 47.049), effective October 1, 2025, through September 30, 2028. The award supports fundamental research into bilingual biopolymers—novel biomolecules that simultaneously encode both nucleic acid and protein information. The research aims to develop methods for controlling the...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Washington University $1,943,750 under the Biomedical Research and Research Training program (CFDA 93.859) to conduct fundamental research on the regulation of the mitotic DNA damage response. The award, effective August 8, 2025, through July 31, 2029, supports investigator-initiated research aimed at understanding how cells regulate DNA repair mechanisms when double-strand breaks occur...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Washington University a Project Grant totaling $388,750 under the Biomedical Research and Research Training program (CFDA 93.859) to conduct fundamental biomedical research investigating phosphatidylserine (PS) signaling mechanisms in apoptotic cell recognition and clearance. The research, performed at the institution's St. Louis, Missouri facility, will operate from March 1, 2026, through...
The Washington University received a $410,520 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded April 1, 2026, with completion targeted for January 31, 2031. The award funds fundamental research investigating the molecular principles of intracellular electrochemistry, specifically examining how living systems establish and maintain buffering environments to support diverse biochemical functions. The research operates at the intersection of physical chemistry and molecular/cell biology to explore electrochemical features of cellular systems, establish theoretical frameworks linking electrochemical properties to cellular function, and correlate chemical environments with disease development. The project delivers scientific research outputs focused on understanding macromolecular condensates and their influence on intracellular electrochemical environments, interfacial electric potentials, and non-enzymatic biochemical processes. Research findings are intended to advance knowledge of intracellular buffering mechanisms, cellular homeostasis, and the regulation of intracellular electrochemistry. The work additionally aims to develop synthetic biology capabilities for studying and engineering cellular functions, with potential applications for disease understanding and bioengineering innovation. Research will be conducted at Washington University's facilities in University City, Missouri, through the Office of Sponsored Research Services.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $410.5k | 3/24/26 |