Project Grant R35GM160156
- The National Institute of General Medical Sciences (NIGMS) awarded a Project Grant totaling $1,385,226 to The Leland Stanford Junior University (Stanford University) under the Biomedical Research and Research Training program (CFDA 93.859). The grant, spanning from September 1, 2023 to August 31, 2026, will support research to map and therapeutically hijack the trafficking of extracellular proteins to the lysosome, a key cellular process involved in regulating cell surface protein function,...
- This $440,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will support research at the Sloan-Kettering Institute for Cancer Research to investigate the mechanisms of lipid droplet protein targeting. The project aims to determine how proteins are targeted to and removed from lipid droplets in human cells, with a focus on understanding the structural basis and physiological...
- The National Institute of General Medical Sciences (NIGMS) awarded a $1,399,125 Project Grant to The Regents of the University of California, doing business as the University of California, Berkeley, under the NIGMS Biomedical Research and Research Training program (CFDA 93.859). The grant aims to decode the molecular processes that regulate circadian rhythms in malaria parasites and discover how disrupting their regulatory networks impacts malaria pathogenesis and transmission. The project will...
- This federal Project Grant award of $394,214 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research on the intracellular transfer of lipids between cell membranes. The grant, awarded to Oregon Health & Science University (OHSU), aims to characterize the lipid transport function of two specific proteins, MPP6 and ATP11A, and determine their 3D structures using cryo-electron microscopy. The...
- The National Institute of General Medical Sciences (NIGMS) awarded a $609,493 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the Sloan-Kettering Institute for Cancer Research. The grant, awarded on June 1, 2025 with a final completion date of May 31, 2030, supports fundamental scientific research to unravel the molecular mechanisms underlying lipid and energy storage in eukaryotic cells. Key objectives include: 1) elucidating the structure, function,...
- This federal Project Grant award of $789,442 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855) supports a multi-omics research study to investigate the role of the myeloid compartment, phagocyte localization, and antibody repertoire in placental malaria immunity. The research team from The Leland Stanford Junior University aims to leverage an extensive biobank of blood and tissue samples from pregnant...
- The National Institute of General Medical Sciences (NIGMS) awarded a $410,256 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Leland Stanford Junior University (Stanford University). This 5-year grant, effective September 15, 2025, aims to integrate physics-based modeling with artificial intelligence to enhance conformational sampling and design of biomolecules, with a focus on understanding self-organization dynamics in biological systems away from...
- This federal Project Grant award of $465,197 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of a next-generation lipidomics platform using advanced mass spectrometry and bioinformatics technologies. The goal is to enable high-throughput lipidomic profiling with high structural specificity to unravel the relationship between lipids and their associated functions in biological...
- This federal Project Grant award of $416,398 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports fundamental scientific research on the regulation of neutral lipid metabolism in eukaryotes. The research program at Texas A&M AgriLife Research, a component of the Texas A&M University System, aims to elucidate the underlying mechanisms controlling the enzymatic activity of acyltransferases...
- This $633,218 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research CFDA Program (93.855), supports research to characterize the mechanism of inhibition of the cholesterol transporter protein Pfncr1 in the malaria parasite. The research aims to use structural, physiological, genetic, and cell biological approaches to investigate two new inhibitors of Pfncr1 that are predicted to bind away from the...
The National Institute of General Medical Sciences (NIGMS) awarded a $385,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Leland Stanford Junior University (Stanford University) to identify and characterize novel lipid transport and processing proteins in Plasmodium, the parasite that causes malaria. The goal is to understand the range of lipids transported by Plasmodium and how its independently evolved lipid transport and processing machinery interfaces with human physiology. This research could provide insights into manipulating lipid transport and processing to improve human health, including in areas such as cardiovascular disease, regulation of hormones, energy homeostasis, and cancer. The grant period runs from Sep 1, 2025 to Jun 30, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $385.0k | 8/27/25 |