Project Grant R35GM157146
- This federal Project Grant award of $435,875.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to understand the coding and noncoding molecular mechanisms of a bifunctional gene in multiple cellular contexts. The award, with a performance period from September 9, 2025 to July 31, 2030, was granted to the Trustees of Indiana University, doing business as Indiana University...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides funding of $370,783 to develop an "Intelligent Droplet Acoustofluidic Platform" for automated liquid-liquid handling and monitoring in biomedical research. The project aims to address challenges with current liquid handling technologies, such as cross-contamination, low throughput, and lack of real-time...
- This federal Project Grant award from the National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $446,435 to support research on the regulatory mechanisms of pterin-dependent signaling in proteobacterial systems. The project, conducted by Trustees of Indiana University (UEI: YH86RTW2YVJ4), will investigate how the cytoplasmic second messenger cyclic diguanylate monophosphate...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is funding the development of new fluorescent imaging probes that can detect and map reactive oxygen and nitrogen species in living cells. The goal is to create a toolkit of probes with different optical characteristics spanning the visible spectrum, enabling multi-color imaging of these oxidative metabolites. This $540,053 award...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $455,940 to the University of Massachusetts Lowell to study the biophysical properties of intrinsically disordered proteins (IDPs) when confined to nanoscale environments. The research aims to reveal how the structural plasticity of IDPs is influenced by their localization and confinement on nanoparticle constructs, with the...
- This federal Project Grant award, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), is funding research on enantioselective chemical synthesis methods using Lewis base and transition metal catalysis. The $631,989 award to the Trustees of Indiana University, awarded on September 5, 2025, aims to develop a general, modular, and operationally trivial toolbox of effective stereoselective reactions by...
- The National Institute of General Medical Sciences (NIGMS) awarded a Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the Massachusetts Institute of Technology (MIT) for $351,010. The grant, with a period of performance from January 1, 2025 to November 30, 2029, focuses on the rational design, synthesis, and characterization of cationic carbone-boracycles as far-red and near-infrared photoactive agents for applications in bioimaging and cancer therapy....
- This federal Project Grant award of $378,672 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) aims to develop a bioorthogonal chemistry-based live-cell imaging technology to study protein lactylation at the spatiotemporal scale. The project, conducted by Bucknell University, will design a fluoro-substituted L-lactic acid metabolic analog that reacts via a novel bioorthogonal fluorine-selenol substitution...
- This federal Project Grant award of $294,060 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to understand biophysical principles of cellular organization at two scales: bacterial communities and intracellular biomolecular condensates. The research aims to elucidate how bacterial quorum sensing operates in natural environments, including the influence of other species, and to investigate...
- The federal Project Grant award of $412,525.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research in the Hundley Lab at Indiana University. The research aims to define the molecular mechanisms that regulate ADAR target recognition and RNA editing, which are essential functions of human ADAR proteins that are dysregulated in over 35 human diseases. The proposed work focuses on understanding...
This federal Project Grant award of $382,026.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to synthesize, characterize, and implement a palette of target-specific organic dyes with biologically-responsive long-lived fluorescence lifetimes. The goal is to develop optical reporting dye technology that can yield two long-lived fluorescence lifetimes that are mechanoresponsive, thermoresponsive, and sensitive to voltage, in order to inform on viscosity, polarity, and voltage changes associated with biological function. This research is being conducted by the Trustees of Indiana University, located in Bloomington, Indiana, and the award period is from September 15, 2025 to August 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $382.0k | 9/12/25 |