Project Grant R01GM160423
- This federal Project Grant award of $382,026.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to synthesize, characterize, and implement a palette of target-specific organic dyes with biologically-responsive long-lived fluorescence lifetimes. The goal is to develop optical reporting dye technology that can yield two long-lived fluorescence lifetimes that are mechanoresponsive,...
- This federal Project Grant award of $304,862 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of the StemFluidics Platform. This innovative educational technology is designed to revolutionize STEM education by providing students with accessible, hands-on microfluidics experiments in the classroom. The StemFluidics Platform features an integrated hardware system with fluid pumps,...
- This federal Project Grant award of $427,625 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop capillaric microfluidics for integrated sample preparation in miniaturized mass spectrometry (mini-MS) systems. The research will focus on creating portable, self-powered, and self-regulated sample preparation capabilities to improve the versatility and applicability of mini-MS instruments for...
- This federal Project Grant award of $435,875.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to understand the coding and noncoding molecular mechanisms of a bifunctional gene in multiple cellular contexts. The award, with a performance period from September 9, 2025 to July 31, 2030, was granted to the Trustees of Indiana University, doing business as Indiana University...
- The National Institute of General Medical Sciences (NIGMS) awarded a $306,872 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Fluid Discovery, Inc., a San Francisco-based biotechnology company, to develop a "Universal Platform for Ultrahigh-Throughput Biocatalyst Evolution with Micro-Mass Spectrometry." The award supports the development of a commercial prototype for Fluid Discovery's novel screening platform, which combines scalable hardware,...
- This federal Project Grant award from the National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $446,435 to support research on the regulatory mechanisms of pterin-dependent signaling in proteobacterial systems. The project, conducted by Trustees of Indiana University (UEI: YH86RTW2YVJ4), will investigate how the cytoplasmic second messenger cyclic diguanylate monophosphate...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA program 93.859 Biomedical Research and Research Training provides $350,000 to Fluidispec LLC to develop a new microfluidic/nanofluidic sample preparation platform. The goal is to improve single-cell and low-input proteomics analysis by enabling efficient extraction of proteins from cells, removal of contaminants, and improved protein denaturation. This platform is expected to enhance...
- The National Science Foundation awarded a $793,276 Project Grant to Indiana University under the Engineering (47.041) federal grant program. The grant will fund the development of next-generation plasmonic nanosensors for ultrasensitive, high-throughput nucleic acid and protein assays from July 1, 2022 to June 30, 2025. Indiana University will construct optical-based biossensors using localized surface plasmon resonance-active metal nanostructures functionalized with photoreversible molecules....
- The federal Project Grant award of $412,525.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research in the Hundley Lab at Indiana University. The research aims to define the molecular mechanisms that regulate ADAR target recognition and RNA editing, which are essential functions of human ADAR proteins that are dysregulated in over 35 human diseases. The proposed work focuses on understanding...
- This federal Project Grant award of $349,566 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of a Spotting-Free Nano-Oscillator Array (SFNOA) technology for high-throughput, label-free quantification of ligand binding kinetics to transmembrane proteins in their native states. The key products and services delivered through this award include: Integration of innovative technologies...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides funding of $370,783 to develop an "Intelligent Droplet Acoustofluidic Platform" for automated liquid-liquid handling and monitoring in biomedical research. The project aims to address challenges with current liquid handling technologies, such as cross-contamination, low throughput, and lack of real-time monitoring and feedback control, by integrating acoustics and microfluidics to manipulate droplets. The platform will leverage artificial intelligence for dynamic regulation of the acoustofluidic actuators through an imaging-based closed-loop feedback control system. The award was granted on September 10, 2025, with a scheduled completion date of August 31, 2029. The work will be performed by the Trustees of Indiana University, a prominent public research university in Bloomington, Indiana.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $370.8k | 9/10/25 |