Project Grant R34DA061049
- This $668,110 Project Grant awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund the development and acceptability testing of a technology-based intervention to reduce cannabis misuse among college students. The project aims to refine an existing intervention that provides information on cannabis products, marketing, laws, and risks to increase young adults' cannabis literacy. The research will involve focus groups with...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Massachusetts General Hospital a $395,280 Project Grant effective July 1, 2025 through June 30, 2030 under the Drug Use and Addiction Research Programs (CFDA 93.279). Dr. Collins will develop and conduct a pilot randomized controlled trial for AMP-C, a digital therapeutic (DTX) designed to address reward dysfunction in individuals with co-occurring Cannabis Use Disorder (CUD) and Major Depressive Disorder...
- Federal Project Grant Award Summary The University of Oregon received a $731,194 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) effective May 15, 2026, with completion by February 28, 2031. This research initiative addresses simultaneous alcohol and cannabis use (SAM) among young adults aged 18-25 through development and testing of a mobile application-based just-in-time intervention (JIT). The project will...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded University of California, Los Angeles a $376,398 Project Grant effective April 15, 2026, through February 28, 2029, under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports the development and preliminary evaluation of a digital therapeutic intervention titled Anxiety Management Treatment for Substance Use Disorders (AMT/SUD), designed to address the clinical gap in treating patients...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Boston Children's Hospital a $489,500 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning June 1, 2025 and concluding May 31, 2027. This research initiative develops and validates remote oral fluid testing procedures to assess cannabis non-use as a key outcome measure in clinical trials targeting younger adults aged 18-30 years with cannabis use disorder (CUD). The project...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Medical University of South Carolina a Project Grant totaling $686,692 under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct prospective research on cannabis use reduction and its impact on patient functioning. Initiated on September 1, 2025, and extending through July 31, 2030, this eight-week clinical trial will enroll 176 adults aged 18 and older with Cannabis Use Disorder...
- This Project Grant from the National Institute on Drug Abuse, part of the Department of Health and Human Services, provides $738,086 to Brown University under the Drug Abuse and Addiction Research Programs (CFDA 93.279) to evaluate a technology-assisted parenting intervention for adolescents in residential substance use treatment. Specifically, the funding supports a randomized controlled trial to test the effectiveness of Parent SMART, a mobile app and telehealth coaching program that...
- Federal Cooperative Agreement Award Summary New York University School of Medicine received $1.37M in federal funding from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and test a telehealth-delivered transcranial direct current stimulation (tDCS) intervention for cannabis use disorder (CUD). The award, granted on July 15, 2025, supports the C.A.R.E.S. (Cannabis Addiction Recovery Enhancement Stimulation) Initiative, which...
- Federal Grant Award Summary The University of Southern California received a $1.5 million Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and pilot test a brief mobile phone-based intervention addressing prenatal cannabis use. The award, effective April 1, 2026 through March 31, 2029, supports a randomized controlled trial designed to reduce cannabis use among pregnant women by delivering evidence-based...
- Federal Grant Award Summary Kaiser Foundation Hospitals' Kaiser Permanente Research Institute received a $681,667 Project Grant award dated April 1, 2026, from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and pilot a just-in-time adaptive intervention (JITAI) targeting e-cigarette and cannabis co-use among young adults in Hawaii. The three-year project (concluding March 31, 2029) will deliver two primary products: (1) an...
FEASIBILITY/ACCEPTABILITY OF A BRIEF MOTIVATIONAL INTERVENTION INTEGRATING ONLINE PERSONALIZED FEEDBACK & TAILORED TEXT MESSAGES FOR FREQUENT/HIGH-INTENSITY CANNABIS USE IN POST-LEGALIZATION LANDSCAPE - ABSTRACT CANNABIS IS A WIDELY USED PSYCHOACTIVE SUBSTANCE AMONG YOUNG ADULTS (YAS), WITH ~44% USING IN THE PAST YEAR. DAILY USE BY YAS NOT ATTENDING COLLEGE (14.5%) IS 3X THE PREVALENCE OF DAILY USE BY COLLEGE ATTENDING PEERS (4.7%). CANNABIS IS ASSOCIATED WITH ACUTE AND LONGER-TERM CONSEQUENCES. A GROWING CONCERN AMONG RESEARCHERS AND CLINICIANS IS OF FREQUENT AND/OR HIGH-INTENSITY USE (I.E., DAILY/NEAR DAILY USE, USE MULTIPLE TIMES A DAY, AND USE OF HIGHER POTENCY THC PRODUCTS). ALTHOUGH PUBLISHED RESEARCH HAS GROWN EXPONENTIALLY IN THE LAST DECADE REGARDING CORRELATES AND CONSEQUENCES OF CANNABIS, DEVELOPMENT AND EVALUATION OF EFFICACIOUS BRIEF INTERVENTIONS TO REDUCE CANNABIS USE IS STILL NEEDED. MOBILE HEALTH (MHEALTH) TECHNOLOGY MAY HELP ADDRESS GAPS BETWEEN CLINICAL NEED AND FORMAL CLINICAL SERVICES, PARTICULARLY FOR NON-TREATMENT SEEKING YAS AND THOSE TYPICALLY UNDERSERVED AND UNDERREPRESENTED IN RESEARCH SUCH AS NON-COLLEGE YAS. THE PROPOSED R34 APPLICATION USES A MULTI-METHOD USER-INFORMED APPROACH TO DEVELOP A NOVEL BRIEF MOTIVATIONAL MHEALTH INTERVENTION THAT INCORPORATES CUTTING-EDGE CANNABIS INTERVENTION RESEARCH. THE PROPOSED INTERVENTION IS AN INTEGRATED MOBILE-ENHANCED WEB-BASED PROGRAM WITH SUBSEQUENT TEXT MESSAGES FOR 5 WEEKS THAT PROVIDES REFLECTION ON YAS' CANNABIS USE IN 5 DOMAINS: (1) PATTERNS/POTENCY OF USE, (2) MOTIVATIONS FOR USE, (3) SOCIAL CONNECTIONS AND USE, (4) PERSONAL USE GOALS AND USE AND (5) PROTECTIVE BEHAVIORAL STRATEGIES. THE INTERVENTION PRIORITIZES AUTONOMY AND WILL ALLOW YAS TO DIRECT THEIR JOURNEY THROUGH THE PROGRAM AND ALLOWING FOR SELF- IDENTIFICATION OF PERSONAL REDUCTION GOALS. YAS ARE AT DIFFERENT PLACES WITH RESPECT TO READINESS TO CHANGE, THUS BY ALLOWING THE YA TO DIRECT THEIR JOURNEY, THE PROGRAM WILL PRESENT APPROPRIATE CONTENT BASED ON THEIR INTERESTS AND TAILORED TO THEIR SELF-EFFICACY AND READINESS TO CHANGE. YAS WILL HAVE OPPORTUNITY TO REFLECT ON MOTIVATIONS FOR USING CANNABIS, AND WHEN APPROPRIATE, COGNITIVE BEHAVIORAL SKILLS-TRAINING FOR SUBSTANCE-FREE STRATEGIES FOR COPING WITH NEGATIVE MOOD AND EMOTIONS, POTENTIAL FOR ENGAGING IN SUBSTANCE-FREE ACTIVITIES, SOCIAL SKILL BUILDING, EXPLORATION OF THE RELATIONSHIPS AMONG VALUES, FUTURE GOALS, AND CANNABIS USE, AND OPPORTUNITIES TO EXPLORE LOWER-RISK USE. AIM 1: DEVELOP A YA CANNABIS INTERVENTION (TAKE 5) TO REDUCE CANNABIS USE AND NEGATIVE CONSEQUENCES AMONG NON-COLLEGIATE YAS ENGAGING IN FREQUENT/HIGH-INTENSITY CANNABIS USE. FOCUS GROUPS AND USER EXPERIENCE INTERVIEWS WILL INFORM THE DEVELOPMENT OF THE INTERVENTION. AIM 2: CONDUCT A 6- MONTH PILOT STUDY WITH NON-COLLEGIATE YAS IN WA (WHO USE CANNABIS 15+ DAYS/MONTH, USE 2+ TIMES PER DAY WHEN USE, OR USE HIGH-POTENCY THC PRODUCTS [60%+]) TO DETERMINE FEASIBILITY AND ACCEPTABILITY. 120 YAS WILL BE RANDOMIZED TO TAKE 5 (N=60) OR ATTENTION CONTROL CONDITION (N=60). THE PRESENT APPLICATION ADDRESSES SEVERAL PRIORITIES IN NIDA'S STRATEGIC PLAN, INCLUDING USING TECHNOLOGY (E.G., SMARTPHONES) TO DELIVER INTERVENTIONS AND INCLUSION OF HIGH-RISK VULNERABLE POPULATIONS (I.E., NON-COLLEGE ATTENDING YAS).
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $116.6k | 5/29/26 | ||
| Not listed | $0 | 11/25/25 | ||
| Not listed | $0 | 11/25/25 | ||
| Not listed | $272.1k | 7/25/25 | ||
| Not listed | $272.1k | 7/25/25 |