Project Grant R34AA032824
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Tennessee Health Science Center a Project Grant of $249,000 on March 10, 2026, under the Alcohol Research Programs (CFDA 93.273) to support a three-year research initiative extending through February 28, 2029. This award funds mechanistic research investigating the role of somatostatin (SST) signaling in the extended amygdala as a potential therapeutic target for comorbid...
- Federal Project Grant Award Summary Spark Biomedical Inc. received a $305,545 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective September 1, 2025, through August 31, 2026. The award funds a one-year research initiative investigating transcutaneous auricular neurostimulation (TAN) as a non-invasive therapeutic intervention for alcohol use disorder (AUD) and alcohol withdrawal syndrome (AWS). TAN...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded The Ohio State University a $692,723 Project Grant on September 18, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct clinical research on orexin receptor antagonism for treating alcohol use disorder (AUD) and stress-related drinking. The award funds a double-blind, placebo-controlled randomized controlled trial (RCT) with 250 treatment-seeking individuals with current AUD,...
- Federal Project Grant Award Summary The University of Virginia received an $800,105 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded September 20, 2025, with completion targeted for August 31, 2028. The award funds development and optimization of CARRII, a digital alcohol-exposed pregnancy (AEP) risk intervention tailored specifically for Native American women. The project addresses documented health...
- Federal Project Grant Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $551,464 to the Palo Alto Veterans Institute for Research on September 20, 2025, to conduct a mechanistic clinical trial assessing the efficacy of deep transcranial magnetic stimulation (DTMS) as a neuromodulation treatment for alcohol use disorder (AUD). The project, which extends through June 30, 2030, will enroll 100 adults with AUD in a randomized, double-blind, sham-controlled study...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded The Ohio State University $474,223 on May 11, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct research on the mechanisms and neuroprotective targets in alcohol-induced brain injury. This project, scheduled for completion by January 31, 2031, aims to elucidate the brain region- and cell-specific mechanisms underlying alcohol-induced developmental neurotoxicity (AIDN) and...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Tennessee Health Science Center a Project Grant totaling $399,076 (awarded September 15, 2025; completion date August 31, 2027) under the Alcohol Research Programs (CFDA 93.273). The project focuses on developing a rapid screening platform for identifying and repurposing FDA-approved drugs to treat alcohol use disorder (AUD) and address chronic alcohol tolerance. Using the...
- Federal Grant Award Summary The Ohio State University received a $593,803 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective September 20, 2025, through June 30, 2030. This research project will conduct mechanistic characterization of JNK2A (c-Jun N-terminal kinase 2A) variants to elucidate the biological pathways underlying alcohol-caused heart failure (ACM). The research will produce fundamental...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $459,343 Project Grant to the University of Pittsburgh under the Alcohol Research Programs (CFDA 93.273) to conduct fundamental neuroscience research examining the mechanisms through which alcohol affects prefrontal cortex circuits, with performance extending from September 20, 2025 through July 31, 2030. The research focuses on understanding how vasoactive intestinal peptide-expressing...
- Federal Project Grant Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA), under its Alcohol Research Programs (CFDA 93.273), awarded $2,365,880 to the University of Tennessee Health Science Center on September 25, 2025, for a research project extending through August 31, 2029. This Project Grant funds fundamental neuroscience research designed to elucidate the neurobiological mechanisms underlying the interaction between social context and alcohol self-administration behavior...
The University of Cincinnati received a $228,118 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective May 1, 2026 through April 30, 2029. This three-year grant funds the development and evaluation of a neurostimulation-based intervention targeting firefighters with co-occurring posttraumatic stress (PTS) symptoms and alcohol use disorders (AUD). The research will develop a Phase II randomized clinical trial protocol testing transcutaneous auricular neurostimulation (TAN) of the vagus nerve as a means to reduce PTS symptoms and associated heavy alcohol use in the firefighter population, utilizing the SPARROW device—a patient-administered, ear-worn electrical stimulation device that stimulates branches of the vagus and trigeminal nerves. The project comprises three coordinated research aims: Year 1 involves protocol development in collaboration with a firefighter community advisory board to create a culturally informed trial design; Year 2 includes a feasibility trial (n=20) evaluating the acceptability, feasibility, and appropriateness of the TAN intervention for firefighters with PTS/AUD; and Year 3 encompasses FDA pre-submission activities, protocol finalization based on FDA feedback, and preparation of a full R01 application for a fully powered Phase II randomized clinical trial. Deliverables include the finalized trial protocol, feasibility study results, FDA submissions, and a competitive R01 grant application to support expanded clinical testing of this intervention approach.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $228.1k | 5/1/26 |