Project Grant R25DC021243
- This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $211,774.00 to the University of Arkansas for Medical Sciences (UAMS) to train the next generation of clinician-scientists to advance access to hearing health in rural and underserved communities. The principal investigator has developed a robust research infrastructure to...
- This $533,978 Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), will support research to uncover the molecular basis of otosclerosis. The project aims to analyze rare and common genomic variants in a large cohort of otosclerosis cases and families, as well as identify epigenetic factors implicated in the disease, using advanced genomic and...
- This federal Project Grant award of $582,552.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), aims to investigate the role of otoferlin in auditory circuit development and explore how gene therapy can restore hearing in patients with congenital deafness caused by otoferlin variants. The project, conducted by The Johns Hopkins University, seeks to understand how the...
- This $620,240 federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports an observational study examining vestibular pathophysiology and dysfunction in patients with sporadic vestibular schwannomas (SVS) and neurofibromatosis type 2-related schwannomatosis (NF2/VS). The study aims to analyze vestibular function, clinical disability, and related...
- This $115,158 Project Grant, awarded on February 1, 2025 by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research into the neurological mechanisms underlying hearing loss. The central hypothesis is that the presentation of phosphatidylserine acts as a signal to mark inactive spiral ganglion neuron connections with outer hair cells for removal, facilitating...
- This $146,206 Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), part of the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), will support research to understand the role of auditory cortex and subcortical regions in learning and retaining associations between sounds and behavioral outcomes in mice. The research aims to investigate how the auditory cortex may train subcortical regions like the medial...
- The federal Project Grant award of $415,743.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research by Oregon Health & Science University (OHSU) on the origins and roles of macrophages in the development, homeostasis, and repair of the tympanic membrane (eardrum). The 5-year project, commencing on February 1, 2025, aims to investigate the fundamental...
- This $369,806 Project Grant from the National Institutes of Health's National Institute on Deafness and Other Communication Disorders will fund research into objective screening tests for noise-induced hearing damage. The University of Wisconsin-Madison will investigate short- and long-term changes in cochlear, afferent, and efferent auditory system function due to noise exposure using otoacoustic emission-based assays of the middle ear muscle reflex and medial olivocochlear reflex....
- This federal Project Grant award, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), will fund a $161,644 multifaceted investigation into speech outcomes following maxillary advancement surgery for individuals with cleft palate. The 5-year study, beginning on July 1, 2025, aims to: 1) investigate anatomical risk factors for post-operative velopharyngeal insufficiency, 2) quantify the relationship...
- This $161,072 Project Grant from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal grant program "Research Related to Deafness and Communication Disorders" (CFDA 93.173), supports research on the role of the FOXP2 transcription factor in the development of the auditory pathway and its potential implications for sensory processing deficits in neurodevelopmental disorders. The research project, conducted by The University of Texas...
RESEARCH TRAINING IN OTOLARYNGOLOGY PROGRAM - PROJECT SUMMARY THE OTOLARYNGOLOGY SPECIALTY REQUIRES A WIDE VARIETY OF EXPERTISE AND SCIENTIFIC STRATEGIES FOR UNDERSTANDING AND TREATING COMMUNICATION DISORDERS. OUR PROGRAM'S GOAL IS TO TRAIN AND DEVELOP PHYSICIANS WHO WILL ADVANCE THE FIELD OF OTOLARYNGOLOGY AND SERVE AS ITS FUTURE INNOVATORS AND LEADERS. WE AIM TO PROVIDE A SOLID FOUNDATION FOR MEDICAL STUDENT AND RESIDENT PARTICIPANTS' FUTURES IN OTOLARYNGOLOGY RESEARCH BY 1) PROVIDING TAILORED MENTORED RESEARCH EXPERIENCES FOR OTOLARYNGOLOGY RESIDENTS AND MEDICAL STUDENTS INTERESTED IN MATCHING WITH OTOLARYNGOLOGY RESIDENCY PROGRAMS; 2) LEVERAGING OUR DIVERSE INSTITUTIONAL RESOURCES TO PROVIDE PROFESSIONAL DEVELOPMENT TRAINING AND RESEARCH SKILL-BUILDING TO PREPARE PARTICIPANTS FOR CLINICIAN-SCIENTIST CAREERS; AND 3) ENHANCING RECRUITMENT OF INDIVIDUALS FROM UNDERREPRESENTED BACKGROUNDS TO CAREERS IN OTOLARYNGOLOGY RESEARCH. WE WILL PROVIDE THE RESEARCH TRAINING, COMMUNICATION, AND PROFESSIONAL SKILLS THAT WILL ENABLE OUR GRADUATES TO BECOME CREATIVE CONTRIBUTORS TO THE FUTURE OF OTOLARYNGOLOGY AND THE TREATMENT OF ASSOCIATED COMMUNICATION DISORDERS. TWO RESIDENTS PER YEAR WILL ENTER INTO 18 CONTINUOUS MONTHS OF RESEARCH TRAINING IN THEIR THIRD YEAR OF RESIDENCY. ADDITIONALLY, 2 MEDICAL STUDENTS PER YEAR WILL BE RECRUITED FOR 9 MONTHS OF RESEARCH TRAINING. THESE STUDENTS WILL BE PAIRED WITH NEAR-PEER RESIDENT MENTORS. THESE TRAINEES CAN CHOOSE FROM A WIDE AND DEEP SELECTION OF RESEARCH THEMES BOTH WITHIN THE DEPARTMENT AND IN ASSOCIATED LABORATORIES AT HOPKINS AND ELSEWHERE. MENTORING TEAMS WILL INCLUDE PRECEPTORS AND CO-PRECEPTORS WITH A HISTORY OF TRAINING CLINICIAN- SCIENTISTS AND EARLY HEALTHCARE PROFESSIONALS, ACADEMIC ACHIEVEMENT, AND COMPETING FOR RESEARCH FUNDING. RESEARCH TOPICS INCLUDE, BUT ARE NOT LIMITED TO: BASIC MECHANISMS OF, AND THERAPEUTIC INNOVATION FOR DIZZINESS AND BALANCE; STUDIES OF THE AUDITORY NERVOUS SYSTEM; PATHOGENESIS OF SINUSITIS, LARYNGOTRACHEAL STENOSIS AND RESPIRATORY PAPILLOMATOSIS; OUTCOMES, QUALITY AND SAFETY IN OTOLARYNGOLOGY; MOLECULAR BIOLOGY AND EPIDEMIOLOGY OF HEAD AND NECK CANCERS; SURGICAL ROBOTICS; AND PUBLIC HEALTH STUDIES IN OTOLARYNGOLOGY-HEAD AND NECK SURGERY. PROGRAM PARTICIPANTS WILL BENEFIT FROM ACCESS TO STATE-OF-THE-ART RESEARCH FACILITIES, A HIGHLY COLLABORATIVE AND DIVERSE RESEARCH ENVIRONMENT, AND SUBSTANTIAL INSTITUTIONAL RESOURCES. PARTICIPANTS WILL ALSO COMPLETE A CURRICULUM FOCUSED ON SAFETY AND COMPLIANCE, RIGOR & REPRODUCIBILITY, RESEARCH SKILL-BUILDING, GRANTSMANSHIP, LABORATORY MANAGEMENT, AND NAVIGATING CAREERS AS CLINICIAN-SCIENTISTS. THE PROGRAM WILL BUILD UPON 33 YEARS OF SUCCESSFUL RESEARCH TRAINING IN OUR T32 PROGRAM, WHICH HAS PRODUCED MANY CLINICIAN-INVESTIGATORS AND LEADERS IN OTOLARYNGOLOGY-HEAD AND NECK SURGERY.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $384.8k | 7/2/25 | ||
| Not listed | $460.2k | 3/13/24 |