Project Grant R24OD036061
Award Date
9/15/24
Completion Date
8/31/28
Dollars Obligated
$744K
Funding Federal Agency
Office of the Director
Awarding Federal Agency
Aggregate Financial Assistance Data
Federal Grant Program
93.351
Assistance Type
Project Grant
Place of Performance
Eugene, OR 97403, USA
Similar Awards
This Project Grant award of $607,682 from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) supports the development of scalable methods for rapid phenotyping and functional testing of genetic variants using zebrafish models. The award to the Oklahoma Medical Research Foundation (OMRF) aims to:
Establish a high-throughput phenotyping pipeline using an 80-mutant knockout library to better understand the pathophysiology of...
This NIH R24 project grant, titled "Multimodal Phenotyping of Zebrafish Models of Human Disease," was awarded by the National Institutes of Health (NIH) Office of the Director under the CFDA 93.351 Research Infrastructure Programs. The $769,325 award to the University of Utah's Office of Sponsored Projects Division will support the development of a comprehensive platform to generate and characterize hundreds of zebrafish disease models. The project will leverage recent technological...
This federal Project Grant award from the National Institutes of Health (NIH) Office of the Director (CFDA 93.351 - Research Infrastructure Programs) provides $1,023,185 to Iowa State University of Science and Technology (Iowa State University) from August 1, 2024 to July 31, 2028 to develop improved genome editing tools and conditional genetic resources for zebrafish research.
The key objectives are to: 1) Expand the zebrafish community resource for Cre recombinase conditional gene studies,...
This Project Grant award from the National Institutes of Health's (NIH) Office of Research Infrastructure Programs (CFDA 93.351 - Research Infrastructure Programs) to Iowa State University of Science and Technology provides $181,754 to develop efficient methods for precisely introducing single nucleotide polymorphisms (SNPs) and variants of uncertain significance (VUS) into the zebrafish genome. The overarching goal is to create an improved gene editing technique called "GenewELD"...
This $337,482 Project Grant was awarded by the National Institutes of Health (NIH) Office of the Director under the NIH Research Infrastructure Programs (CFDA 93.351) on June 15, 2024. The grant will enable the modernization of the aging zebrafish research facility at The Ohio State University's Bevis Hall. Key objectives include:
Automating the monitoring and control of critical water parameters and feeding to increase research reproducibility, reduce waste, and shorten generation time of...
This federal Project Grant award for $162,461, provided by the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172), supports an integrated multimodal phenotyping study of zebrafish models of human cognitive disorders. The University of Utah is the prime awardee and will leverage their expertise in single-cell biology, data science, and developmental biology to rapidly generate and characterize knockouts of 61 transcriptional regulators...
This Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) provides $629,508 to the University of Texas at Austin to generate animal models of mitochondrial DNA (mtDNA) disease. The project aims to develop designer zebrafish models harboring specific mtDNA variants to enable new approaches for diagnosing and treating mitochondrial disorders, which have a minimum prevalence of 1 in 5,000 adults and few effective...
This Project Grant award from the National Institutes of Health under the Research Infrastructure Programs (CFDA 93.351) provides $198,750.00 to the University of Texas at Austin to establish conditional animal models of mitochondrial DNA (mtDNA) disease using zebrafish. The project aims to develop a novel CRISPR-based system to enable precise edits to the mitochondrial genome, allowing for temporal and spatial control of mtDNA variations. This will enable the creation of the first...
This $144,928 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports a Ph.D. student's research and training at the University of Oregon. The grant funds two years of fellowship support to enable the student to use computational and quantitative imaging approaches to study the mechanisms of cell state transitions underlying organ size control during zebrafish fin regeneration. The research...
This $1,344,373 Project Grant award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) supports research to investigate cardiac regeneration in human cells and zebrafish models. The primary objectives are to: (I) assess the dynamic gene regulatory networks involved in zebrafish heart regeneration using single-cell ATAC-seq, (II) interrogate the reactivation of developmental gene programs in human cardiac organoids after injury using...