Project Grant R24EY039196
- The National Eye Institute awarded the University of California, Los Angeles $244,150 on April 15, 2026, under the Vision Research program (CFDA 93.867) to support a project grant investigating molecular gradients underlying wiring plasticity in the visual cortex. The research combines single-cell transcriptomics, epigenomics, connectomics, and computational analysis to link genes, cell types, regulatory networks, and circuit structure in layers 2 and 3 (L2/3) glutamatergic neurons in the...
- The National Eye Institute awarded The Regents of the University of California, San Francisco $1,356,963 on September 17, 2025, under the Vision Research program (CFDA 93.867) to establish three resource and service modules supporting vision research through advanced tools and computational infrastructure. The Ocular Structure and Function module provides NEI R01 investigators with ocular phenotyping capabilities including morphological analysis, light and electron microscopy, ocular imaging,...
- The National Eye Institute awarded the University of California, Berkeley $143,031 on December 4, 2025, under the Vision Research program (CFDA 93.867) to computationally model the role of spatial phase in the selectivity and invariance of responses in primary visual cortex (V1) and secondary visual cortex (V2) to intermediate-level features in natural images. The modeling-driven research will investigate how phase-related computations operate across V1 and V2 and generate testable predictions...
- The National Eye Institute awarded the University of California, Santa Barbara $117,840 on March 8, 2026, under the Vision Research program (CFDA 93.867) to support research on retinotopic-to-egocentric transformation in visuoparietal cortex. The award funds a Project Grant investigating how the brain transforms visual object representations from a retinotopic reference frame (based on retinal photoreceptor topography) to an egocentric reference frame (mapped relative to the animal's head or...
- The National Eye Institute awarded the University of California, Los Angeles $132,173 on May 1, 2026, under the Vision Research program (CFDA 93.867) to support research linking physiology, computation, and circuitry in primate visual cortex. The project funds development of experimental and analytical approaches to understand canonical computations—fundamental processing patterns underlying neural functions across hierarchical brain networks—by studying marmoset early visual areas V1 and V2....
- The National Eye Institute awarded The Regents of the University of California, San Francisco $737,998 on July 1, 2026, under the Vision Research program (CFDA 93.867) to define area-specific cellular and circuit-level specialization in the human temporal cortex. The project will identify electrophysiological, morphological, and synaptic features unique to excitatory neurons in the human inferior temporal gyrus and test how cortical neurons and local circuits are specialized for object...
- The National Eye Institute awarded the University of California, Davis $287,457 on July 1, 2026, under the Vision Research program (CFDA 93.867) to develop and validate machine learning models predicting treatment response, disease activity, and complications risk in patients with non-infectious uveitis. The recipient will extract detailed ocular examination data from electronic health records and build predictive tools for integration into clinical workflows, providing clinicians with real-time...
- The National Institutes of Health National Eye Institute awarded a $1.792 million Cooperative Agreement to the University of California, Los Angeles on September 1, 2026, under the Vision Research program (CFDA 93.867). The award funds development of adeno-associated virus vectors incorporating cell-type-specific cis-regulatory modules to target 23 distinct retinal cell types in primates, enabling precise labeling and functional manipulation of specific cells. The project aims to dissect...
- The National Eye Institute, part of the Department of Health and Human Services National Institutes of Health, awarded $624,743 to the Regents of the University of California, doing business as University of California, Berkeley, on May 1, 2026, under the Vision Research program (CFDA 93.867). The award funds research into the function and regulation of constitutive prostaglandin D2 and DP receptor signaling in retinal health and neurodegeneration. The research investigates the physiological and...
- The National Eye Institute awarded the University of California Irvine $431,750 on May 1, 2026, under the Vision Research program (CFDA 93.867) to explore novel mechanisms of obstructive meibomian gland dysfunction. The research tests the hypothesis that alterations in meibum lipid synthesis cause obstructive meibomian gland dysfunction, leading to duct dilation and psoriasis-like epithelial inflammatory disease. The work involves confirming that human meibomian gland epithelial cell (HMGEC)...
The National Eye Institute awarded the University of California Irvine $388,206 on September 1, 2026, under the Vision Research program (CFDA 93.867) to develop VisionKB, a single-cell multi-omics knowledgebase for the visual system. The award funds three specific deliverables: construction of a curated single-cell multi-omics reference atlas of the eye; development of a code-free, collaborative data-analysis platform; and delivery of an AI-powered co-pilot for automated data access and interactive analysis. VisionKB will organize, curate, and integrate large-scale single-cell multi-omics data—including scRNA-seq, snATAC-seq, and spatial transcriptomics—from the visual systems of humans and other species. The platform will enable researchers without computational expertise to interact with, explore, and analyze data through an intuitive interface, support integration of user-generated data, and enable construction of custom analyses. The framework is intended to be readily applicable to other organ systems and datasets. Performance occurs in Irvine, California, with a period of performance extending from September 1, 2026, through May 31, 2030. This is a Project Grant, a form of assistance funding.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $388.2k | 9/1/26 |