Project Grant R21NS145182
Award Date
7/1/25
Completion Date
6/30/27
Dollars Obligated
$226K
Federal Agency
National Institute of Neurological Disorders and Stroke
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Minnesota, USA
Similar Awards
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $423,500.00 to investigate cerebellar nuclei dysfunction in Spinocerebellar Ataxia Type 1 (SCA1). The research aims to determine how the cerebellar nuclei function is altered throughout SCA1 progression, how mutant ataxin-1 impacts the cerebellar nuclei, and how changes...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $233,280 to support a 5-year research initiative led by Dr. Srinivasan at the University of Michigan. The research plan aims to investigate the mechanisms by which exercise can improve the abnormal firing of Purkinje neurons, a key driver of motor deficits in spinocerebellar...
The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services, awarded a $4,528,840 Project Grant to The Salk Institute For Biological Studies under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The three-year award beginning August 19, 2022 will fund research to functionally dissect cerebellar output circuits that orchestrate limb motor control. Specifically, the grantee will...
This $195,570 federal Project Grant award was made by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research by The Regents of the University of California, San Francisco (UCSF) to investigate the role of the molecular co-chaperone DNAJC7 in preventing the aggregation of misfolded proteins associated with neurodegenerative diseases such as...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $478,732 to Seattle Children's Hospital to characterize the cellular and molecular features of human cerebellar progenitor zones. The research leverages expertise in human cerebellar development and access to fetal tissue to conduct in vitro assays, live imaging, and...
This Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research aimed at developing therapies to restore circuit function in cerebellar degeneration. The $605,523 award to The Trustees of Columbia University will fund a 5-year study to investigate how the loss of Purkinje cell synapses differentially contributes to cerebellar...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $183,751 to the Regents of the University of Minnesota to develop and deploy a miniaturized ultra-widefield micro-camera array microscope (MCAM) capable of imaging large areas of the cerebellar cortex in freely behaving mice with cellular resolution. The project aims to...
This federal Project Grant award of $985,026 from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders, aims to investigate the roles and mechanisms of epitranscriptomic regulation in the development and function of the mammalian nervous system, as well as the pathological consequences of disrupting these processes. The research program will utilize mouse models and human induced...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,341,874 project grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF). The grant supports research focused on elucidating the molecular mechanisms that control dendrite development, as well as studying mechanosensation and regeneration in Drosophila dendritic arborization (DA) neurons. Key...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $770,502 to The Regents of the University of California, San Francisco to conduct research on a model of cerebral small vessel disease. The goal is to understand the molecular mechanisms by which collagen IV regulates TGF-beta signaling, perform intravital imaging of the...