The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, awarded a $296,151 Project Grant to Insoma Bio, Inc. to investigate the use of the company's proprietary Fractomer biomaterial to improve outcomes after peripheral nerve repair. The funding will support research to tailor the Fractomer formulation for peripheral nerve applications and evaluate its...
The University of New Hampshire (UNH) was awarded a $426,509 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The grant, awarded on September 21, 2023, will fund the development of an injectable microporous hydrogel for delivering neural stem cells to regenerate damaged neural tissues, such as from spinal cord injuries. The key products...
This $638,718 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop and validate innovative techniques for selective, targeted neurostimulation of peripheral nerves. The key products and services to be delivered include: Testing the hypothesis that interferential current stimulation (I2CS) can selectively activate specific nerve...
Renerva LLC, a for-profit manufacturer, is developing peripheral nerve matrix (PNM) technologies to facilitate functional recovery in animal models of direct muscle neurotization (DMN) through a $494,955 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853). The two-year project aims to 1) optimize the formulation of a clinical-grade PNM product to provide...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $419,038 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program to the University of North Dakota. The purpose of this 3-year grant, awarded on September 17, 2024, is to develop a miniature selective plane illumination fluorescence microscope for high-resolution volumetric imaging of astrocyte activity in freely behaving mice. The...
The University of Nebraska Medical Center (UNMC) was awarded a $1,544,999.00 Project Grant by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to conduct research on a "NOVEL ER STRESS MITIGATION PATHWAY IN ERBB2-DRIVEN ONCOGENESIS". The grant, which has a performance period from May 1, 2024 to April 30, 2027, will support UNMC's investigation of an innovative pathway for mitigating endoplasmic reticulum (ER) stress in ErbB2-driven...
This $500,000 Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) supports research to develop bioprinted tissue scaffolds with Schwann cell density gradients and electrical conductivity for peripheral nerve regeneration. The goal is to understand how Schwann cell distribution and electrical properties within the scaffolds can enhance the repair of injured peripheral nerves. The primary recipient, Cleveland State University, will use bioprinting...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $6,522,833 Project Grant to The Leland Stanford Junior University to conduct a mechanistic randomized clinical trial investigating the central and peripheral nervous system mechanisms of pain relief induced by peripheral nerve stimulation (PNS) for the treatment of refractory chronic neuropathic pain. The 3-year study, funded under the NIH HEAL Initiative's CFDA 93.279 Drug Abuse and Addiction Research Programs, aims...
The U.S. Department of Defense's Defense Health Agency awarded a $393,416 Project Grant to the Board of Regents of the University of Nebraska Medical Center (UNMC) under the Military Medical Research and Development program (CFDA 12.420). The grant, with a performance period from September 1, 2024 to August 31, 2026, will support UNMC's research on the "Influence of Ocular Blast Injury on Retinal Output Synapses in the Brain". This project aims to advance the understanding of the...
The University of Nebraska-Lincoln (UNL) received a three-year, $415k Project Grant from the National Science Foundation (NSF) under the Engineering (47.041) federal grant program. The grant funds an undergraduate research opportunities site in biomedical engineering devices at UNL from May 2021 through April 2024. The site will provide hands-on research experiences for undergraduate students in biomedical engineering device design and development. Through participation in the site, students...