Project Grant R21MH142995
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $433,125 Project Grant to the University of California, Los Angeles to investigate inter-brain synchrony as a neural mechanism underlying social connection in individuals with schizophrenia. The two-year project, which commenced September 1, 2025 and concludes August 31, 2027, under the Mental Health Research Grants program (CFDA 93.242), represents the first direct investigation of inter-brain synchrony in...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant totaling $433,125 to the University of California, Los Angeles (UCLA) under the Mental Health Research Grants program (CFDA 93.242), with an award date of September 18, 2025 and completion date of September 17, 2027. The project, titled "Investigating the Asymmetrical Development of EBF1+ Cells in the Central Amygdala and Its Functional Consequences," delivers basic neuroscience...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $800,384 to The Regents of the University of California, San Francisco on March 10, 2026, under the Mental Health Research Grants program (CFDA 93.242). This award supports basic neuroscience research investigating the molecular and functional mechanisms of prefrontal-hippocampal long-range inhibition, with a project completion date of December 31, 2030. The research specifically dissects...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of California, Los Angeles $117,263 under the Mental Health Research Grants program (CFDA 93.242) on May 6, 2026, for a K99/R00 Pathway to Independence Award concluding April 30, 2028. This award supports the development of individualized novel phenotyping and predictive models for risk and resilience in psychosis and bipolar spectrum disorders (PBSD). The research synthesizes data from...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of California, Los Angeles a Project Grant of $424,433 under the Mental Health Research Grants program (CFDA 93.242) to develop practical frameworks and implementation tools for improving participant engagement in brain-computer interface (BCI) early feasibility studies. The award, effective March 1, 2026 through December 31, 2029, will produce two primary deliverables: a comprehensive framework for...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Leland Stanford Junior University a Project Grant totaling $160,272 under the Mental Health Research Grants program (CFDA 93.242) for the period of June 1, 2025, through May 31, 2027. This research project, titled "Theta Burst Modulation of Hippocampal-Cortical Rhythms in Schizophrenia," investigates whether connectivity-guided theta burst stimulation (TBS) can alter hippocampal neural activity and...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded UCLA a $125,556 Project Grant (CFDA 93.242: Mental Health Research Grants) beginning October 25, 2025, and concluding November 30, 2028, to conduct basic neuroscience research investigating the neuronal mechanisms underlying avoidance and pursuit behaviors during human ambulatory navigation. The research leverages a unique cross-institutional collaboration utilizing epilepsy patients with implanted...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $121,933.00 to the University of California, San Diego under the Mental Health Research Grants program (CFDA 93.242) for the period of June 1, 2025 through May 31, 2027. This research project will deliver scientific investigation into compartment-specific synaptic organization and plasticity in layer 2/3 pyramidal neurons during learning in behaving animals. The research employs cutting-edge...
- Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $832,307 Project Grant to The Regents of the University of California, San Francisco on April 24, 2026, under the Mental Health Research Grants program (CFDA 93.242). This award funds basic neuroscience research investigating the genetic control and developmental mechanisms of basal telencephalic structures, specifically examining how the medial ganglionic eminence (MGE) generates gamma-aminobutyric acid (GABA)ergic...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $818,253 to The Regents of the University of California, San Francisco under the Mental Health Research Grants program (CFDA 93.242) beginning July 1, 2025, and extending through April 30, 2030. This Project Grant supports a five-year research investigation examining neuromodulatory system abnormalities in late-life depression (LLD), with specific focus on the associations between structural and functional brain...
Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $408,843 to the University of California, Los Angeles under the Mental Health Research Grants program (CFDA 93.242) on April 25, 2026, for a project period extending through March 31, 2028. This Project Grant funds basic neuroscience research investigating the mechanistic relationship between autonomic nervous system (ANS) dysfunction and disrupted brain activity in patients with first-episode schizophrenia. The research examines how physiological cycles—specifically high-frequency heart rate variability (HF-HRV) associated with parasympathetic nervous system activity—interact with and modulate brain oscillations through phase-amplitude coupling, a well-established mechanism of oscillatory organization in the brain. The project will generate scientific insights into brain-body interactions and their contributions to cognitive dysfunction in schizophrenia through comparative analysis of first-episode schizophrenia patients and healthy control individuals. Expected products include peer-reviewed publications, mechanistic data on heart-to-brain coupling effects on electroencephalography (EEG) oscillations, and findings that may inform understanding of the relationship between autonomic dysregulation and cognitive impairment in psychiatric illness. The research addresses a critical gap in knowledge regarding whether ANS dysfunction causally contributes to disorganized brain activity and impaired cognitive processes in schizophrenia, with potential implications for developing targeted physiological and clinical interventions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $408.8k | 4/28/26 |