Project Grant R21MH141228
- The National Institute of Mental Health awarded The Feinstein Institutes for Medical Research $795,165 on June 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate microRNAs in neural-derived extracellular vesicles as diagnostic and treatment response biomarkers in first-episode schizophrenia. The research addresses the clinical gap in schizophrenia diagnosis and treatment assessment, which currently relies on psychiatric interviews without reliable biomarkers to...
- The National Institute of Mental Health awarded New York University $435,974 on May 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop computational models that quantify individual differences in learning and decision-making and predict psychiatric symptoms. The award funds development of a novel computational framework combining recurrent neural networks and dynamical systems theory to model reward learning processes at the individual level rather than group...
- The National Institute of Mental Health awarded $1.579 million to the Research Foundation For Mental Hygiene, Inc., operating as the New York State Psychiatric Institute, on July 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to fund basic neuroscience research into the circuit mechanisms by which early-life adversity produces sustained reward deficits. The research examines how childhood trauma—including abuse, neglect, and chronic stress—alters neural circuits governing...
- The National Institute of Mental Health awarded The Trustees of Columbia University in the City of New York $534,191 on April 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop robust fine-mapping tools for genetic discovery in neuropsychiatric traits using deep phenotype data from diverse populations. The project addresses the challenge of understanding genetic causes of complex neuropsychiatric conditions including autism spectrum disorders, bipolar disorder, and...
- This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $334,588 to the Beth Israel Deaconess Medical Center (BIDMC) from April 1, 2025 to March 31, 2027. The project, titled "HIVE MIND: Harnessing Collective Intelligence for Predicting Clinical High-Risk for Psychosis Outcomes," aims to develop and refine predictive analytical methods, leveraging artificial intelligence and collective...
- The National Institute of Mental Health awarded the Research Foundation For Mental Hygiene, Inc. $477,335 on July 8, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct broadband near infrared spectroscopy research elucidating the role of cortical brain cytochrome c oxidase activity in the pathophysiology of bipolar disorder. The recipient, operating through its New York State Psychiatric Institute division, will use broadband near infrared spectroscopy to directly...
- The National Institute of Mental Health awarded The Trustees of Columbia University in the City of New York $244,428 on August 20, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct research on cholinergic modulation of thalamocortical projections to prefrontal cortex in cognitive flexibility. The research will determine whether acute adult cholinergic modulation in the prefrontal cortex modulates attentional set-shifting performance and whether enhancing...
- The National Institute of Mental Health awarded $195,804 to the Research Foundation For Mental Hygiene, Inc. (operating through its New York State Psychiatric Institute division) on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct a project grant studying care transitions and discharge practices for clients of Assertive Community Treatment (ACT) programs. The research identifies client characteristics that predict psychiatric hospitalization risk during...
- The National Institute of Mental Health awarded Icahn School of Medicine at Mount Sinai $462,000 on August 14, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop a novel spatial transcriptomics platform and investigate RNA-binding protein function in human neurons as it relates to schizophrenia risk. The award funds two primary aims. The first develops a spatial RNA-protein interactome MERFISH (SPRIM) platform to visualize endogenous RNA-protein interactions at...
- The National Institute of Mental Health awarded New York University $1.694 million on June 5, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct bioinformatic and experimental research on long non-coding RNAs (lncRNAs) in stress response and psychiatric disorder resilience. The research integrates genetic, transcriptional, and epigenetic datasets to identify lncRNAs mediating stress susceptibility and resilience in the brain. The project involves two primary aims:...
The National Institute of Mental Health awarded The Feinstein Institutes For Medical Research $460,625 on July 24, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct network analysis research on clinical high risk for psychosis populations. The award funds a research project examining the interplay of clinical symptoms, neurocognition, functioning, and stressful events in individuals at clinical high risk for developing psychosis using network theory. The research applies network modeling to over 2,000 clinical high risk individuals to map how clinical symptoms, neurocognitive deficits, social functioning, and environmental stressors interact to accelerate illness progression. The project identifies central and influential factors driving transition to psychosis, with the goal of informing development of targeted, precision interventions. Work is performed in Manhasset, New York. The period of performance runs from July 24, 2026, through July 23, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $460.6k | 7/27/26 |