Project Grant R21MH142900
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $394,200 to the Research Foundation For Mental Hygiene, Inc. (through its New York State Psychiatric Institute division) under the Mental Health Research Grants program (CFDA 93.242) on August 1, 2025, for a five-year project period extending through July 31, 2030. This Project Grant funds a clinical research study examining the role of the anterior hippocampus in major depressive disorder (MDD) pathogenesis....
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Broad Institute of MIT and Harvard a $475,388 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to conduct basic neuroscience research investigating the transcriptional and neuro-immune consequences of KDM5B loss in bipolar disorder (BD). The award, initiated June 16, 2025, and extending through June 15, 2027, supports a two-year research initiative examining how genetic...
- Federal Grant Award Summary Brigham and Women's Hospital Inc., operating through its Department of Faulkner Pathology, received a $185,220 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award, effective June 1, 2025, through May 31, 2030, supports a five-year research initiative investigating the behavioral, neural, and molecular correlates of response inhibition in bipolar disorder (BD). The research employs...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $789,593 Project Grant to the Research Foundation For Mental Hygiene, Inc. (operating as the New York State Psychiatric Institute) under the Mental Health Research Grants program (CFDA 93.242) for the period of July 1, 2026 through March 31, 2031. This research initiative investigates the circuit mechanisms underlying reward deficits induced by early-life adversity (ELA), addressing a significant risk factor for...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $778,548 to the Research Foundation For Mental Hygiene, Inc. (Nathan S Kline Institute Division) on September 19, 2025, under the Mental Health Research Grants program (CFDA 93.242) to support a five-year research project examining sensory contributions to third visual pathway (TVP) dysfunction in schizophrenia. The project, extending through July 31, 2030, investigates the neural mechanisms underlying social...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded HealthPartners Institute a $199,747 K23 Mentored Research Grant (CFDA 93.242: Mental Health Research Grants) on April 8, 2026, for a five-year project period through March 31, 2031. The award funds the development of machine learning-based predictive models using electronic health record (EHR) and administrative data to identify young people with bipolar disorder at risk for severe mood episodes. The research...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $843,322 to the Research Foundation For Mental Hygiene, Inc. (operating as the New York State Psychiatric Institute) on March 5, 2026, under the Mental Health Research Grants program (CFDA 93.242). This Project Grant supports longitudinal positron emission tomography (PET) imaging research investigating antipsychotic medication binding to the dopamine-3 receptor (D3R) in individuals with schizophrenia. The...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Rochester a $423,500 Project Grant under the Mental Health Research Grants program (CFDA 93.242) on May 5, 2025, with a completion date of May 4, 2027. This award supports research investigating visual perception and predictive processing dysfunction in schizophrenia and related psychiatric disorders. The research employs high-density electroencephalography (EEG) and innovative visual...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $534,191 Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) effective April 1, 2026, through December 31, 2030, under the Mental Health Research Grants program (CFDA 93.242). The award funds research on genetic discovery for neuropsychiatric traits using deep phenotype data. The project addresses a critical gap in psychiatric genetics by developing novel...
- The National Institute of Mental Health (NIMH) awarded a $1,737,000 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Max Planck Florida Corp, doing business as Max Planck Florida Institute For Neuroscience. The 3-year project, starting September 1, 2024, aims to systematically investigate the synaptic energy logistics that enable the brain to process and store information. Specifically, the research will discover novel regulators that dictate the flexibility of...
The National Institute of Mental Health (NIMH) awarded a $477,335 Project Grant (CFDA 93.242: Mental Health Research Grants) to the Research Foundation for Mental Hygiene, Inc., operating through its New York State Psychiatric Institute division, effective July 8, 2026, through July 7, 2028. This research initiative will employ Broadband Near Infrared Spectroscopy (BNIRS), a novel non-invasive optical neuroimaging technique, to directly measure cytochrome c oxidase (OxCOX) signal as an indicator of mitochondrial activity in the brains of bipolar disorder patients and healthy volunteers. The study will investigate whether reduced brain mitochondrial activity correlates with bipolar disorder pathophysiology, particularly depression severity. The project will generate research outputs examining the relationship between brain mitochondrial dysfunction and systemic mitochondrial abnormalities by correlating brain OxCOX measurements with peripheral blood-based markers of mitochondrial health (Mitochondrial Health Index), developed by co-investigator Martin Picard. Additionally, the research will assess potential associations between mitochondrial pathology and other disease factors including life stress exposure and mood episode history. As BNIRS is low-cost and non-invasive, findings from this basic research may advance understanding of bipolar disorder's underlying pathophysiology and inform future treatment strategies for this major public health condition.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $477.3k | 7/10/26 |