Project Grant R01MH138770
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $394,200 to the Research Foundation For Mental Hygiene, Inc. (through its New York State Psychiatric Institute division) under the Mental Health Research Grants program (CFDA 93.242) on August 1, 2025, for a five-year project period extending through July 31, 2030. This Project Grant funds a clinical research study examining the role of the anterior hippocampus in major depressive disorder (MDD) pathogenesis....
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded Children's Research Institute a Project Grant of $654,005 under CFDA 93.242 (Mental Health Research Grants) on June 1, 2026, with a completion date of March 31, 2031. This award funds basic neuroscience research investigating the function of the paralaminar nucleus of the amygdala (PL) from adolescence to early adulthood using mouse models. The research seeks to advance understanding of how late-maturing...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded Massachusetts Institute of Technology a $803,849 Project Grant effective June 3, 2026, through March 31, 2031, under the Mental Health Research Grants program (CFDA 93.242). This award supports basic neuroscience research investigating the functional architecture of the brain's reward system through advanced neuroimaging techniques. The project delivers research products comprising circuit-specific...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Trustees of Columbia University in the City of New York a Project Grant totaling $126,900 under the Mental Health Research Grants program (CFDA 93.242). The award, dated April 2, 2026, with completion targeted for March 31, 2028, supports fundamental neuroscience research investigating cellular and circuit mechanisms underlying value representation in the mouse medial prefrontal cortex (mPFC). The...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $827,879 Project Grant to Icahn School of Medicine at Mount Sinai on March 25, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate ghrelin receptor and striosomal interactions in stress-induced decision-making through December 31, 2030. The research examines how chronic stress exposure alters neural circuits and endocrine mechanisms that contribute to abnormal cost-benefit...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $778,548 to the Research Foundation For Mental Hygiene, Inc. (Nathan S Kline Institute Division) on September 19, 2025, under the Mental Health Research Grants program (CFDA 93.242) to support a five-year research project examining sensory contributions to third visual pathway (TVP) dysfunction in schizophrenia. The project, extending through July 31, 2030, investigates the neural mechanisms underlying social...
- Federal Project Grant Award Summary Award Details: This Project Grant, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), was granted to Emory University on November 8, 2026, with a total obligation of $100,228 and an anticipated completion date of May 13, 2029. The award funds basic neuroscience research investigating neural circuit mechanisms underlying reward-seeking behaviors. Research Scope and Deliverables: The funded...
- Federal Project Grant Award Summary New York University received a $435,974 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), effective May 1, 2026 through April 30, 2028. The award funds development of a novel computational framework combining very small recurrent neural networks (RNNs) and dynamical systems theory to model individual learning and decision-making processes in a flexible yet interpretable...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $194,400 Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) under the Mental Health Research Grants program (CFDA 93.242), effective May 18, 2026, with a completion date of May 17, 2031. This five-year award supports research investigating the neural mechanisms underlying cognitive flexibility—the capacity to adjust behavior in response to environmental or...
- Federal Project Grant Award Summary New York University received a $710,563 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded March 5, 2026, with completion targeted for November 30, 2030. This grant supports fundamental neuroscience research investigating the neural circuit mechanisms underlying dynamic learning rates in reinforcement learning. The research will elucidate how orbitofrontal cortex (OFC)...
The National Institute of Mental Health (NIMH) awarded a Project Grant totaling $789,593 to the Research Foundation For Mental Hygiene, Inc. (operating as the New York State Psychiatric Institute) under the Mental Health Research Grants program (CFDA 93.242). The award, dated July 1, 2026, and scheduled for completion by March 31, 2031, funds basic neuroscience research investigating the circuit mechanisms underlying early-life adversity (ELA)-induced reward deficits. The research employs advanced neurobiological techniques, including fiber-photometry and optogenetics, to examine how disruptions in ventral pallidum-nucleus accumbens (VP-NAC) neural circuit activity mediates persistent reward-processing deficits in mice exposed to early-life adversity. This work addresses a significant gap in understanding how childhood trauma produces sustained neurobiological changes that increase vulnerability to psychiatric disorders including depression, substance use disorders, and schizophrenia. The project delivers fundamental research outputs contributing to NIMH's mission of transforming understanding and treatment of mental illnesses through basic and clinical investigation. By dissecting the specific reward constructs and neural mechanisms affected by early-life adversity, the research aims to advance knowledge of the neurobiological pathways linking childhood adversity to adult psychopathology, with potential implications for developing targeted interventions addressing reward-related psychiatric symptoms.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $789.6k | 6/26/26 |