This Project Grant award of $781,464 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports the development of a "Causal Wiring Diagram of Transdiagnostic Brain Functions" at Brigham & Women's Hospital in Boston, MA. The study aims to systematically map causal brain circuitry connected to transcranial magnetic stimulation (TMS) sites that modulate a range of behaviors relevant to mental illness, including transdiagnostic behaviors and diagnosis-specific symptoms. The research will leverage highly-sampled resting-state fMRI and cutting-edge brain stimulation protocols to create a multidimensional atlas of causal brain circuitry that can inform the selection of appropriate TMS targets for treating specific patient symptoms. This 5-year project includes a sub-award to Acacia Mental Health to collect behavioral, TMS, and MRI data in collaboration with Brigham & Women's Hospital and Harvard University.
Generated 3/4/25, 7:45 AM