Project Grant R21MH135410
- This $136,890 federal Project Grant award from the National Institute of Mental Health (CFDA 93.242 Mental Health Research Grants) supports research at Boston College to enhance the understanding of the neurobiology underlying behavioral responses to danger signals. The key objectives are to identify and describe a dorsal raphe nucleus (DRN) to insula tract responsible for responding to danger signals and executing appropriate behavioral responses in males and females. The research will...
- This federal Project Grant award of $132,462 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is funding research at Yale University to understand the neural substrates underlying the encoding of temporal threat proximity and temporally accurate defensive responses to threat. The research seeks to determine the roles of norepinephrine, second messengers, and prefrontal neurons in encoding threat proximity information and...
- This federal Project Grant award was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to The Regents of the University of California, San Francisco (UCSF). The $781,119 award, with a performance period from March 1, 2025 to December 31, 2029, will support research to understand the neural population dynamics and circuit mechanisms in the ventral hippocampus that represent conditioned and unconditioned stimuli during...
- This federal Project Grant award for $633,438, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to develop a data-driven framework for real-time neural control using patterned microstimulation. The research aims to investigate the principles governing multi-electrode microstimulation in the primate prefrontal cortex, and introduce a novel data-driven algorithm to predict optimal stimulation patterns. The...
- This federal Project Grant award of $125,556 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award will support research to identify neuronal mechanisms in the medial temporal lobe that underlie avoidance and pursuit behaviors during naturalistic human navigation tasks. The study will leverage a collaboration with epilepsy patients who have implanted electrodes to record single-unit and local field potential...
- This federal Project Grant award of $2,908,921.00, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to understand the neural mechanisms underlying associative learning and reinforcement in the midbrain. The project, conducted by researchers at the University of Michigan, utilizes 2-photon calcium imaging to study the activity of neurons in the inferior colliculus (IC) region of the mouse midbrain during...
- This Project Grant award, valued at $120,015.00, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award supports research by the President and Fellows of Harvard College to develop a novel technological pipeline that enables the monitoring of large-scale neural activity in freely moving animals and the identification of the transcriptomic identity of the same individual neurons. This research aims to achieve a...
- This federal Project Grant award of $136,050.00, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to investigate how a specific protein, BTBD11, regulates the function and composition of glutamatergic synapses in interneurons. The research aims to elucidate the role of BTBD11 and liquid-liquid phase separation in maintaining the unique properties of glutamatergic synapses in interneurons, which are...
- The University of Washington received a $618,863 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to investigate the neural dynamics of fear circuits in rodent models of risk and trauma. The 5-year project, starting April 1, 2025, aims to leverage an established "approach food-avoid predator" paradigm in rats to study the fear circuit mechanisms involved in risky decision-making within spatial environments...
- This federal Project Grant award of $677,261 was provided by the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), to the University of New Mexico (UNM) Health Sciences Center. The award will fund research to examine how the locus coeruleus, a brain region responsible for noradrenergic signaling, regulates hippocampal network activity and behavioral flexibility during learning. The project aims to elucidate the neural mechanisms by which...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $426,250 in funding to Trustees of Boston College to support research on the neural circuit basis of safety learning. The research aims to investigate how interconnected brain regions like the basolateral amygdala, insular cortex, and infralimbic prefrontal cortex work together to process safety signals and mediate safety learning and fear inhibition. The project period runs from July 10, 2024 to July 9, 2026. The findings are expected to advance the understanding of the neural mechanisms underlying safety learning and provide insights into abnormal safety-related behavior in psychopathology.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $426.3k | 7/8/24 |