This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 - Mental Health Research Grants provides $375,927 to the University of Virginia to study the impact of premature birth and serotonin signaling on the development of prefrontal cortex circuits and cognitive function. The project will use a combination of in vivo electrophysiology, optogenetics, chemogenetics, confocal imaging, and behavioral assays to mechanistically determine how critical neonatal...
This Project Grant award from the National Institute of Mental Health (NIMH), under the federal Mental Health Research Grants program (CFDA 93.242), provides $1,406,795.00 in funding to Duke University to conduct research on microglial-serotonin interactions in the developing brain. The research aims to determine the mechanisms by which microglia, a type of immune cell, target serotonin-producing neurons for removal in male but not female offspring in conditions of maternal high-fat diet. The...
This is a Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) for the project titled "EARLY LIFE STRESS AND DIFFERENTIAL EFFECTS ON THE MOLECULAR MATURATION OF SPECIFIC SUBTYPES OF BRAIN SEROTONIN NEURONS". The $466,125 grant was awarded on August 25, 2023 to President And Fellows Of Harvard College, acting through the Harvard Medical School Division, to investigate the impact of early life stress and...
This $711,897 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to explore the neural mechanisms underlying the modulation of aggressive and prosocial behaviors by serotonin. The key objectives are to: 1) characterize the temporal dynamics of serotonin's effects on aggression and prosocial behavior; 2) identify the specific neuronal subpopulations in the nucleus accumbens that mediate...
This federal Project Grant award, issued by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), is funding research to investigate the neural mechanisms underlying social information processing and representation. The total award amount is $829,966.00 over the project period from August 16, 2024 to May 31, 2029. The research aims to elucidate how diverse social information, such as familiarity and hierarchy, is integrated in the brain...
This Project Grant award from the National Institute of Mental Health (NIMH), under CFDA program 93.242 Mental Health Research Grants, will support research into the neurocircuitry underlying motivated reward-seeking behavior as a coping mechanism for stress. The $606,029 award, effective August 1, 2024 through July 31, 2025, will be administered by the University of Massachusetts Medical School. The key objectives are to investigate how sub-populations of neurons in the medial...
The National Institute of Mental Health (NIMH) awarded a Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the Research Foundation For Mental Hygiene, Inc. (RFMH) for the project "Building a Granular Brain-wide Map of the Serotonin System." The $2,331,491 award, with a project period from May 2024 to February 2029, aims to map the brain-wide projections of serotonergic neurons with single-cell resolution, determine the strength and functional connectivity...
This federal Project Grant award of $885,500 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research to identify the specific cell types within the extended amygdala and nucleus accumbens that modulate social approach and avoidance behaviors. The research team from the University of California, Davis will utilize the FLICRE system to label neurons activated during social behaviors, and then leverage single-cell RNA...
This Project Grant award from the National Institute of Mental Health (NIMH), under CFDA program 93.242 Mental Health Research Grants, provides $135,989 to The Trustees of Princeton University to comprehensively map the influence of gonadal hormones on network-level neural coding of proactive social behavior and related variables in mice. The goal is to unravel the neuroendocrine mechanisms underlying social behavior and its dysfunction in mood disorders. The project develops new computational...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $816,063 to The Trustees of Columbia University in the City of New York to study the neural mechanisms underlying how social stimuli elicit motivated behavior. The research aims to elucidate the physiological response properties of the anterior cingulate cortex (ACC) and basolateral amygdala (BLA) circuits in mediating motivated behavior...