Project Grant R21HD122069
- The National Institute of Child Health and Human Development, part of the National Institutes of Health, awarded the University of Illinois $110,228 on December 3, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to develop a markerless motion-capture tool for objectively evaluating motor impairments in stroke survivors. The project, titled "Action Likelihood to Evaluate Weakness, Abnormal Motor Synergies, and Spasticity in Stroke Survivors,"...
- The National Institute of Child Health and Human Development awarded The Medical College of Wisconsin, Inc., $1,318,677 on September 15, 2025, under the Child Health and Human Development Extramural Research program (CFDA 93.HDR) to conduct research on the muscle metaboreflex mechanism in stroke survivors. The research investigates why stroke survivors cannot adequately increase and sustain cardiovascular drive during exercise, limiting their capacity to exercise at high intensity. The project...
- The National Institute of Child Health and Human Development awarded The Spaulding Rehabilitation Hospital Corporation $170,640 on July 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to support a K23 career development award investigating childhood stroke predictors of motor recovery. The award funds a physician-scientist's career development and research program centered on neurorecovery mechanisms in pediatric acquired brain injury, with...
- The National Institute of Child Health and Human Development awarded the University of Utah $667,666 on June 3, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to conduct a multimodal intervention study combining transcranial random noise stimulation with functional electrical stimulation-assisted task-specific practice to promote motor recovery and upper-extremity function in stroke survivors with chronic moderate-to-severe impairment. The...
- The National Institute of Child Health and Human Development awarded Virginia Polytechnic Institute & State University $454,240 on August 15, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to conduct a longitudinal study measuring changes in peripheral nerve signaling following stroke. The research will examine whether brain lesions disrupt peripheral nerve function responsible for tactile perception, a gap in current understanding of...
- The National Institute of Child Health and Human Development awarded New York University $179,495 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate movement anxiety in stroke patients during inpatient rehabilitation. The research will prospectively track upper extremity movement anxiety in subacute stroke patients using the Tampa Scale of Kinesiophobia, clinical scales, electronic health record data, and wrist-worn...
- The National Institute of Child Health and Human Development awarded The Trustees of The University of Pennsylvania $444,470 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.HDR) to develop a learning-from-demonstration framework enabling rehabilitation robots to automatically learn optimal assistance patterns from expert therapist demonstrations while adapting to individual patient capabilities in stroke neurorehabilitation. The research...
- The National Institute on Aging awarded the University of Maryland, Baltimore $649,688 on May 15, 2026, under the Aging Research program (CFDA 93.866) to develop microinstrumented cortical organoid therapy for chronic stroke treatment. The award funds research on brain organoid transplantation combined with flexible bioelectronic monitoring to enable real-time electrophysiology and intravital multiphoton imaging of implanted organoids in stroke-damaged adult brain tissue. Current stroke...
- The National Institute of Child Health and Human Development awarded Northwestern University $440,287 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct the Stroke Training to Advance Balance During Locomotor Experiences (STABLE) trial, a five-year clinical trial examining gait rehabilitation strategies for people with chronic stroke. The project develops and tests a cable-driven robotic system that creates a movement...
- The National Institute of Child Health and Human Development awarded $676,469 to the University of Pittsburgh on July 10, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) for development and validation of artificial intelligence–driven rehabilitation prescription tools for stroke patients. The project develops natural language processing algorithms to extract rehabilitation information from free-text electronic health record data and creates predictive...
The National Institute of Child Health and Human Development awarded the University of Maryland, Baltimore $433,595 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a proof-of-concept study examining whether blood flow restriction combined with low-intensity resistance training enhances force generation and motor performance in stroke survivors with upper extremity paresis. The study will enroll thirty-two participants with upper extremity weakness following unilateral stroke and measure muscle strength, reach-to-grasp performance, and neuromuscular adaptations following an eight-week blood flow restriction–low-intensity resistance training intervention. The research will assess adaptations in the corticospinal, corticoreticulospinal, and spinal pathways and measure muscle cross-sectional area. The work addresses a clinical gap: traditional high-intensity resistance training (loads exceeding 70% of one-repetition maximum) carries risks of musculoskeletal injury and abnormal synergistic movement in stroke survivors, leading clinicians to prescribe low-intensity resistance training despite its lesser effectiveness for improving force generation. Blood flow restriction during low-intensity resistance training has demonstrated strength improvements in neurotypical adults comparable to high-intensity training and may unlock similar gains for this population. Performance occurs in Baltimore, Maryland. The period of performance runs from September 1, 2026, through August 31, 2028. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $433.6k | 8/26/26 |