Project Grant R21HD115800
- The U.S. National Institute of Child Health and Human Development (NICHD) awarded a $766,982 Project Grant to Carnegie Mellon University under the Child Health and Human Development Extramural Research program (CFDA 93.865). The project aims to develop and validate a novel computational framework to simulate uteroplacental hemodynamics and placentation, with the goal of identifying metrics for early detection of pregnancy complications related to abnormal placental formation. This research...
- The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
- The National Institute of Child Health and Human Development (NICHD), through the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded a $604,153 Project Grant to Northwestern University to build machine learning models to identify placental causes of stillbirth. The project aims to perform detailed analysis of clinical, obstetric, and laboratory data from 1,500 stillbirth cases to classify the cause of demise, with the goal of improving the ability to identify...
- This $1,367,400 Cooperative Agreement, awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports the UC San Diego Center for Stillbirth Prevention in conducting research on maternal and placental determinants of fetal growth restriction (FGR). The goal is to develop a maternal serum-based test for antepartum identification of placental dysfunction and FGR, which are...
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support a multi-faceted initiative to address stillbirth, a devastating pregnancy outcome that affects 1 in 160 pregnancies in the U.S. annually. The $661,258 award to the University of Washington will be used to: improve clinical evaluation and data collection for stillbirth, advance tools to evaluate...
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- This $525,531 federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) aims to validate and optimize a predictive model for assessing individual pregnancy risk of placental dysfunction, a leading cause of preventable stillbirths in the United States. The grant recipient, Oregon Health & Science University, will externally validate the existing predictive model and evaluate the...
- The National Institute of Child Health and Human Development (NICHD) awarded a $411,125 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Syracuse University to develop a microfluidic human placenta organoid model. The goal is to generate human trophoblast stem cells (HTSCs) from induced pluripotent stem cells and use them to create a placenta organoid system that can replicate early/mid-gestation placental development. The researchers will study the role of...
- This $429,000 federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the gene and environmental influences on placental angiogenesis and severe fetal growth restriction. The University of Colorado-Denver, the awardee organization, will leverage induced pluripotent stem cell technology to better...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $1,500,138 to examine early-life mortality trends in the United States between 1990 and 2024. The project aims to provide detailed insights into how changes in cause-specific death rates have impacted early-life survival chances for different U.S. birth cohorts, and how these...
The National Institute of Child Health and Human Development (NICHD) awarded a $423,500 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Wayne State University. The grant, titled "Placenta-Specific Maternal Plasma Proteomic Biomarkers of Fetal Death", aims to profile maternal plasma proteins as predictive biomarkers for fetal death, which currently affects 5.73 per 1,000 births in the U.S. with significant disparities among racial and ethnic groups. The study will leverage the Wayne State University Perinatal Biobank to generate a placenta-specific plasma protein signature that can predict fetal death in asymptomatic patients earlier in gestation, potentially enabling preventive interventions. The award period is from August 1, 2025 to July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $423.5k | 7/30/25 |