Project Grant R01HD116699
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support a multi-faceted initiative to address stillbirth, a devastating pregnancy outcome that affects 1 in 160 pregnancies in the U.S. annually. The $661,258 award to the University of Washington will be used to: improve clinical evaluation and data collection for stillbirth, advance tools to evaluate...
- The National Institute of Child Health and Human Development (NICHD) awarded a $423,500 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Wayne State University. The grant, titled "Placenta-Specific Maternal Plasma Proteomic Biomarkers of Fetal Death", aims to profile maternal plasma proteins as predictive biomarkers for fetal death, which currently affects 5.73 per 1,000 births in the U.S. with significant disparities among...
- This $525,531 federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) aims to validate and optimize a predictive model for assessing individual pregnancy risk of placental dysfunction, a leading cause of preventable stillbirths in the United States. The grant recipient, Oregon Health & Science University, will externally validate the existing predictive model and evaluate the...
- This $1,367,400 Cooperative Agreement, awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports the UC San Diego Center for Stillbirth Prevention in conducting research on maternal and placental determinants of fetal growth restriction (FGR). The goal is to develop a maternal serum-based test for antepartum identification of placental dysfunction and FGR, which are...
- The U.S. National Institute of Child Health and Human Development (NICHD) awarded a $766,982 Project Grant to Carnegie Mellon University under the Child Health and Human Development Extramural Research program (CFDA 93.865). The project aims to develop and validate a novel computational framework to simulate uteroplacental hemodynamics and placentation, with the goal of identifying metrics for early detection of pregnancy complications related to abnormal placental formation. This research...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $1,330,985 Cooperative Agreement to Oregon Health & Science University (OHSU) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award, with a performance period from September 1, 2025 to July 31, 2030, aims to identify the effects of allostatic load (chronic stress exposure) and maternal dietary patterns on pregnancy outcomes and placental health....
- The Collaborative Action for Research to End Stillbirth (CARES) Cooperative Agreement, funded by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 Child Health and Human Development Extramural Research, will conduct innovative, integrated research to develop and implement strategies for improved prediction and prevention of stillbirth, with a focus on addressing racial disparities. The $1,243,868 award to the Trustees of Columbia University will establish a...
- The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
- The National Institute of Child Health and Human Development (NICHD) awarded a $434,500 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Research Institute at Nationwide Children's Hospital. The grant, titled "NEOGX-III: Interpretable Machine Learning with Integrated Analysis of Maternal & Infant Electronic Medical Records for Unbiased Prediction of Need for Genome Sequencing in Level III NICUs," aims to develop a machine...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865) provides $313,180.00 to Amahealth LLC to develop an AI-powered method for accurately predicting the onset of labor in pregnant women. The 8-month project aims to enhance the team's existing work by using deep learning on maternal physiological data from wearable sensors to...
The National Institute of Child Health and Human Development (NICHD), through the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded a $604,153 Project Grant to Northwestern University to build machine learning models to identify placental causes of stillbirth. The project aims to perform detailed analysis of clinical, obstetric, and laboratory data from 1,500 stillbirth cases to classify the cause of demise, with the goal of improving the ability to identify underlying factors that lead to stillbirths, which currently account for 30-40% of cases. The research will test the machine learning models using an additional 500 stillbirth cases from the Mayo Clinic to assess generalizability, with the potential to pilot the models in lower-resource settings. Improving the understanding of stillbirth causes can provide important benefits for patient grieving, risk assessment for subsequent pregnancies, and targeted treatment development. The award period runs from September 1, 2025 to May 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $604.2k | 8/29/25 |