This $1,829,617 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will fund research at the University of California, San Diego (UCSD) to develop stem cell-based models for studying placental defects associated with early-onset preeclampsia. The key objectives are to: 1) identify optimal stem cell methods for studying abnormal trophoblast (placental cell)...
This Project Grant award, valued at $1,454,109 and running from July 1, 2024 to April 30, 2029, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research to investigate the physiological and genetic mechanisms underlying placental responses to hypoxia and their impact on fetal growth and development. The key research activities include: Generating cell...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $442,550 to quantify altered placental microstructure and correlate microstructural changes with preeclampsia. The awardee, The Administrators of the Tulane Educational Fund (Tulane University), will develop quantitative ultrasound (QUS) methods to characterize the human placenta ex vivo and...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) is focused on developing and testing an innovative approach to reduce inflammation-associated preterm birth. The $635,254 award to the University of Texas Medical Branch at Galveston will fund research to evaluate the safety, stability, and efficacy of extracellular vesicle-mediated delivery of the...
The National Institute of Child Health and Human Development (NICHD) awarded a $191,965 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the University of Texas at Austin to conduct research aimed at identifying and validating the key transcription factors that drive preeclampsia-specific gene expression programs. The research will utilize human trophoblast stem cell differentiation as a model system to elucidate the molecular mechanisms underlying...
This federal Project Grant award, funded by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research, is focused on developing non-invasive liquid biopsy screening methods for early detection and prediction of preterm birth, preeclampsia, and intrauterine growth restriction. The $717,871 grant was awarded on Aug 13, 2024 to the Magee-Womens Research Institute and Foundation in Pittsburgh, PA. The research aims...
This federal Project Grant award, totaling $429,000.00 and granted by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to assess placental vascularization development using contrast-enhanced ultrasound (CEUS) imaging. The research aims to determine if the SHAPE (Subharmonic Aided Pressure Estimation) technique can serve as a safe, noninvasive, and real-time tool to...
This Project Grant award, totaling $293,756, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The primary objective is to enhance understanding of placental dysfunction in common obstetric disorders such as preeclampsia, preterm birth, and fetal growth restriction. The research will leverage placental multi-omics data analysis to define placental physiological association...
This Project Grant award from the Department of Health and Human Services National Institutes of Health National Institute of Child Health and Human Development provides $769,916 to Emergent Biotechnologies LLC for research into a novel therapy for preeclampsia. The funding supports Phase 1 of developing and characterizing a handle region peptide as an innovative treatment for preeclampsia under the Child Health and Human Development Extramural Research program (CFDA 93.865). Phase 1 work will...
The National Institute of Child Health and Human Development (NICHD) awarded a $461,780 R21 project grant (CFDA 93.865: Child Health and Human Development Extramural Research) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2023 to investigate the feasibility of a clinical-scale, anticoagulation-free artificial placenta device. The project aims to overcome key barriers to the clinical translation of artificial placenta technology, which is designed to simulate...