Project Grant R21GM160870
- This federal Project Grant award of $349,566 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of a Spotting-Free Nano-Oscillator Array (SFNOA) technology for high-throughput, label-free quantification of ligand binding kinetics to transmembrane proteins in their native states. The key products and services delivered through this award include: Integration of innovative technologies...
- This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $442,106.00 to Florida International University (FIU) to develop a new sensing mechanism and approach for a nanopore sensor that will enable ultrasensitive and selective detection of various small molecules under physiological conditions. The project aims to create a portable, inexpensive, and easy-to-use sensor applicable to areas such as protein analysis, pharmaceutical research,...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $396,854 to develop innovative nanopore tweezer tools for analyzing the structural dynamics and conformational states of disease-associated kinases. The research aims to track kinase movements in real-time at a 100-microsecond resolution, generating comprehensive energetic maps of kinase behavior during substrate...
- The U.S. National Institute of General Medical Sciences (NIGMS), through the Biomedical Research and Research Training federal grant program (CFDA 93.859), awarded a $432,834 Project Grant to the Board of Regents of the University of Nebraska on April 15, 2025. The grant supports the development of an "enzyme-free, label-free quantitative microarray technology" to detect and quantify target nucleic acids, such as microRNA, with high sensitivity down to the attomolar (10^-18 M) range....
- This federal Project Grant award of $427,625 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop capillaric microfluidics for integrated sample preparation in miniaturized mass spectrometry (mini-MS) systems. The research will focus on creating portable, self-powered, and self-regulated sample preparation capabilities to improve the versatility and applicability of mini-MS instruments for...
- This $305,000 STTR Phase I Project Grant awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program aims to develop an ultra-sensitive biosensor capable of protein analysis at single-molecule resolution. The biosensor consists of a nanopatterned chip with a proprietary scaffold material that binds and immobilizes molecular targets, which are then detected using surface-enhanced Raman spectroscopy (SERS). This innovation seeks...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859), is focused on developing a novel high-throughput, high-content imaging platform for analyzing extracellular vesicles (EVs) at the single-particle level. The $298,999 award to Numentus Technologies Inc. will fund the construction, testing, and application of this platform to detect and characterize EV subpopulations, including...
- The National Institute of General Medical Sciences (NIGMS) awarded a $306,872 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Fluid Discovery, Inc., a San Francisco-based biotechnology company, to develop a "Universal Platform for Ultrahigh-Throughput Biocatalyst Evolution with Micro-Mass Spectrometry." The award supports the development of a commercial prototype for Fluid Discovery's novel screening platform, which combines scalable hardware,...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $350,000 to Electronic Biosciences, Inc. to develop the first technology capable of high-accuracy sequencing of the RNA modifications pseudouridine (Ps) and N6-methyladenosine (M6A) using nanopore sequencing. The project aims to merge innovative bisulfite adduct methodology with Electronic Biosciences' enzyme-free, multipass...
- The National Institute of Standards and Technology (NIST) awarded a $955,000 Project Grant under the Congressionally-Identified Projects program (CFDA 11.617) to HMH Hospitals Corporation in Edison, NJ. The grant establishes a nanopore long-read DNA sequencing capability as a core facility within the HMH Center for Discovery and Innovation. Specific equipment and technologies to be procured include the PromethION high-throughput and GridION medium-throughput sequencing systems, along with...
This Project Grant award of $316,250 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is to support the development of a novel solid-state nanopore array chip technology by Molariti Inc. in Cambridge, MA. The goal is to create a breakthrough in nanopore fabrication that can enable highly sensitive, high-throughput, and quantitative biomolecule analysis for applications such as early disease detection, biomarker discovery, and personalized medicine. The project period runs from Sep 1, 2025 to Aug 31, 2027. This investment aims to drive advancements in biomedical research tools that can significantly improve healthcare by providing more accurate and efficient methods for identifying and analyzing biomolecules from complex samples.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $13.8k | 9/9/25 | ||
| Not listed | $302.5k | 8/25/25 |